| Name | UHMK1 |
| ID | Q8TAS1 |
| Role | kinase |
| Enzymatic Domains |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| UHMK1 | MBP | Ser299 | GRDSRSGsPMARR | phosphorylation down-regulates | 10880969 | SIGNOR-78895 |
| UHMK1 | MBP | Ser299 | GRDSRSGsPMARR | phosphorylation down-regulates | 16401070 | SIGNOR-143485 |
| UHMK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 19033656 | SIGNOR-182489 |
| UHMK1 | SYN1 | Ser438 | GSHGQTPsPGALPLG | phosphorylation unknown | 10880969 | SIGNOR-78899 |
| UHMK1 | PAM | Ser946 | DRLSTEGsDQEKEDD | phosphorylation unknown | 10574929 | SIGNOR-247009 |
| UHMK1 | CDKN1B | Ser10 | NVRVSNGsPSLERMD | phosphorylation up-regulates | 10831586 | SIGNOR-77705 |
| UHMK1 | CDKN1B | Ser10 | NVRVSNGsPSLERMD | phosphorylation up-regulates | 12093740 | SIGNOR-90274 |
| UHMK1 | SF1 | Ser80 | PPNPEDRsPSPEPIY | phosphorylation up-regulates | 16420481 | SIGNOR-143837 |
| UHMK1 | SF1 | Ser82 | NPEDRSPsPEPIYNS | phosphorylation up-regulates | 16420481 | SIGNOR-143841 |
| UHMK1 | SF1 | Ser80 | PPNPEDRsPSPEPIY | phosphorylation up-regulates | 23175611 | SIGNOR-199793 |
| UHMK1 | SF1 | Ser82 | NPEDRSPsPEPIYNS | phosphorylation up-regulates | 23175611 | SIGNOR-199797 |
| UHMK1 | PIMREG | Ser131 | GAQKGSGsPTHSLSQ | phosphorylation up-regulates | 23419774 | SIGNOR-192702 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| UHMK1 | phosphorylation up-regulates → | MBP PSer299 | phosphorylation down-regulates ⊣ | MBP | 10880969 | SIGNOR-78895 |
| UHMK1 | phosphorylation up-regulates → | MBP PSer299 | phosphorylation down-regulates ⊣ | MBP | 16401070 | SIGNOR-143485 |
| UHMK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 19033656 | SIGNOR-182489 |
| UHMK1 | phosphorylation up-regulates → | SYN1 PSer438 | phosphorylation down-regulates ⊣ | SYN1 | 10880969 | SIGNOR-78899 |
| UHMK1 | phosphorylation up-regulates → | PAM PSer946 | phosphorylation down-regulates ⊣ | PAM | 10574929 | SIGNOR-247009 |
| UHMK1 | phosphorylation up-regulates → | CDKN1B PSer10 | phosphorylation up-regulates → | CDKN1B | 10831586 | SIGNOR-77705 |
| UHMK1 | phosphorylation up-regulates → | CDKN1B PSer10 | phosphorylation up-regulates → | CDKN1B | 12093740 | SIGNOR-90274 |
| UHMK1 | phosphorylation up-regulates → | SF1 PSer80 | phosphorylation up-regulates → | SF1 | 16420481 | SIGNOR-143837 |
| UHMK1 | phosphorylation up-regulates → | SF1 PSer82 | phosphorylation up-regulates → | SF1 | 16420481 | SIGNOR-143841 |
| UHMK1 | phosphorylation up-regulates → | SF1 PSer80 | phosphorylation up-regulates → | SF1 | 23175611 | SIGNOR-199793 |
| UHMK1 | phosphorylation up-regulates → | SF1 PSer82 | phosphorylation up-regulates → | SF1 | 23175611 | SIGNOR-199797 |
| UHMK1 | phosphorylation up-regulates → | PIMREG PSer131 | phosphorylation up-regulates → | PIMREG | 23419774 | SIGNOR-192702 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| UHMK1 | phosphorylation down-regulates | MBP | SIGNOR-78895 |
| UHMK1 | phosphorylation down-regulates | MBP | SIGNOR-143485 |
| UHMK1 | phosphorylation down-regulates | STMN1 | SIGNOR-182489 |
| UHMK1 | phosphorylation → unknown | SYN1 | SIGNOR-78899 |
| UHMK1 | phosphorylation → unknown | PAM | SIGNOR-247009 |
| UHMK1 | phosphorylation → up-regulates | CDKN1B | SIGNOR-77705 |
| UHMK1 | phosphorylation → up-regulates | CDKN1B | SIGNOR-90274 |
| UHMK1 | phosphorylation → up-regulates | SF1 | SIGNOR-143837 |
| UHMK1 | phosphorylation → up-regulates | SF1 | SIGNOR-143841 |
| UHMK1 | phosphorylation → up-regulates | SF1 | SIGNOR-199793 |
| UHMK1 | phosphorylation → up-regulates | SF1 | SIGNOR-199797 |
| UHMK1 | phosphorylation → up-regulates | PIMREG | SIGNOR-192702 |