| Name | MAPK15 |
| ID | Q8TD08 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 13-304 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK15 | MAPK15 | Tyr177 | EDQAVTEyVATRWYR | phosphorylation up-regulates | 16336213 | SIGNOR-142973 |
| MAPK15 | MAPK15 | Thr175 | GPEDQAVtEYVATRW | phosphorylation up-regulates | 16336213 | SIGNOR-142969 |
| PTPN1 | MAPK15 | Tyr177 | EDQAVTEyVATRWYR | dephosphorylation down-regulates | 16336213 | SIGNOR-142981 |
| PPP2CA | MAPK15 | Thr175 | GPEDQAVtEYVATRW | dephosphorylation down-regulates | 16336213 | SIGNOR-142977 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK15 | phosphorylation up-regulates → | MAPK15 PTyr177 | phosphorylation up-regulates → | MAPK15 | 16336213 | SIGNOR-142973 |
| MAPK15 | phosphorylation up-regulates → | MAPK15 PThr175 | phosphorylation up-regulates → | MAPK15 | 16336213 | SIGNOR-142969 |
| PTPN1 | dephosphorylation down-regulates ⊣ | MAPK15 PTyr177 | dephosphorylation up-regulates → | MAPK15 | 16336213 | SIGNOR-142981 |
| PPP2CA | dephosphorylation down-regulates ⊣ | MAPK15 PThr175 | dephosphorylation up-regulates → | MAPK15 | 16336213 | SIGNOR-142977 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK15 | phosphorylation → up-regulates | MAPK15 | SIGNOR-142973 |
| MAPK15 | phosphorylation → up-regulates | MAPK15 | SIGNOR-142969 |
| PTPN1 | dephosphorylation down-regulates | MAPK15 | SIGNOR-142981 |
| PPP2CA | dephosphorylation down-regulates | MAPK15 | SIGNOR-142977 |