| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK3 | CABLES1 | Ser273 | PGQGGSTsAFEQLQR | phosphorylation unknown | 11733001 | SIGNOR-250679 |
| AKT1 | CABLES1 | Thr309 | APLRRCRtLSGSPRP | phosphorylation down-regulates activity | 25361894 | SIGNOR-276756 |
| CDK5 | CABLES1 | Ser313 | RCRTLSGsPRPKNFK | phosphorylation unknown | 11733001 | SIGNOR-112418 |
| AKT1 | CABLES1 | Thr415 | AFGARRNtIDSTSSF | phosphorylation down-regulates activity | 25361894 | SIGNOR-276757 |
| CyclinE1/CDK3 | CABLES1 | Ser273 | PGQGGSTsAFEQLQR | phosphorylation unknown | 11733001 | SIGNOR-273183 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK3 | phosphorylation up-regulates → | CABLES1 PSer273 | phosphorylation down-regulates ⊣ | CABLES1 | 11733001 | SIGNOR-250679 |
| AKT1 | phosphorylation up-regulates → | CABLES1 PThr309 | phosphorylation down-regulates ⊣ | CABLES1 | 25361894 | SIGNOR-276756 |
| CDK5 | phosphorylation up-regulates → | CABLES1 PSer313 | phosphorylation down-regulates ⊣ | CABLES1 | 11733001 | SIGNOR-112418 |
| AKT1 | phosphorylation up-regulates → | CABLES1 PThr415 | phosphorylation down-regulates ⊣ | CABLES1 | 25361894 | SIGNOR-276757 |
| CyclinE1/CDK3 | phosphorylation up-regulates → | CABLES1 PSer273 | phosphorylation down-regulates ⊣ | CABLES1 | 11733001 | SIGNOR-273183 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK3 | phosphorylation → unknown | CABLES1 | SIGNOR-250679 |
| AKT1 | phosphorylation → down-regulates activity | CABLES1 | SIGNOR-276756 |
| CDK5 | phosphorylation → unknown | CABLES1 | SIGNOR-112418 |
| AKT1 | phosphorylation → down-regulates activity | CABLES1 | SIGNOR-276757 |
| CyclinE1/CDK3 | phosphorylation → unknown | CABLES1 | SIGNOR-273183 |