| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ITK | HAVCR2 | Tyr265 | IRSEENIyTIEENVY | phosphorylation up-regulates activity | 17069754 | SIGNOR-273644 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ITK | phosphorylation up-regulates → | HAVCR2 PTyr265 | phosphorylation up-regulates → | HAVCR2 | 17069754 | SIGNOR-273644 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ITK | phosphorylation → up-regulates activity | HAVCR2 | SIGNOR-273644 |
