Entity Details

Name NEK7
ID Q8TDX7
Role kinase
Enzymatic Domains
Protein kinase 34-299
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
NEK7KIF11Ser1033GINTLERsKVEETTEphosphorylation
up-regulates activity
29899413SIGNOR-273890
NEK7TERF1Ser114AIIHGLSsLTACQLRphosphorylation
up-regulates activity
28216227SIGNOR-278447
NEK7TERF1Ser114AIIHGLSsLTACQLRphosphorylation
up-regulates quantity
28216227SIGNOR-278448
NEK7TERF1Ser114AIIHGLSsLTACQLRphosphorylation
up-regulates quantity by stabilization
28216227SIGNOR-273903
NEK7KIF14Ser1217PIKNLHSsHSSGLMDphosphorylation
up-regulates activity
28630147SIGNOR-266420
NEK7KIF14Ser1219KNLHSSHsSGLMDKSphosphorylation
up-regulates activity
28630147SIGNOR-266419
NEK7KIF14Ser1220NLHSSHSsGLMDKSSphosphorylation
up-regulates activity
28630147SIGNOR-266418
NEK7KIF14Ser56NDDPLLRsAGKVRDIphosphorylation
up-regulates activity
28630147SIGNOR-266416
NEK7KIF14Ser607NLIDLAGsERCSTAHphosphorylation
up-regulates activity
28630147SIGNOR-266417
NEK7EML4Ser144QSPQIRAsPSPQPSSphosphorylation
down-regulates activity
31409757SIGNOR-279237
NEK7EML4Ser146PQIRASPsPQPSSQPphosphorylation
up-regulates activity
31409757SIGNOR-273884
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
NEK7phosphorylation
up-regulates
KIF11
PSer1033
phosphorylation
up-regulates
KIF1129899413SIGNOR-273890
NEK7phosphorylation
up-regulates
TERF1
PSer114
phosphorylation
up-regulates
TERF128216227SIGNOR-278447
NEK7phosphorylation
up-regulates
TERF1
PSer114
phosphorylation
up-regulates
TERF128216227SIGNOR-278448
NEK7phosphorylation
up-regulates
TERF1
PSer114
phosphorylation
up-regulates
TERF128216227SIGNOR-273903
NEK7phosphorylation
up-regulates
KIF14
PSer1217
phosphorylation
up-regulates
KIF1428630147SIGNOR-266420
NEK7phosphorylation
up-regulates
KIF14
PSer1219
phosphorylation
up-regulates
KIF1428630147SIGNOR-266419
NEK7phosphorylation
up-regulates
KIF14
PSer1220
phosphorylation
up-regulates
KIF1428630147SIGNOR-266418
NEK7phosphorylation
up-regulates
KIF14
PSer56
phosphorylation
up-regulates
KIF1428630147SIGNOR-266416
NEK7phosphorylation
up-regulates
KIF14
PSer607
phosphorylation
up-regulates
KIF1428630147SIGNOR-266417
NEK7phosphorylation
up-regulates
EML4
PSer144
phosphorylation
down-regulates
EML431409757SIGNOR-279237
NEK7phosphorylation
up-regulates
EML4
PSer146
phosphorylation
up-regulates
EML431409757SIGNOR-273884
Regulator Mechanism/Effect Target SIGNOR-ID
NEK7phosphorylation

up-regulates activity
KIF11SIGNOR-273890
NEK7phosphorylation

up-regulates activity
TERF1SIGNOR-278447
NEK7phosphorylation

up-regulates quantity
TERF1SIGNOR-278448
NEK7phosphorylation

up-regulates quantity by stabilization
TERF1SIGNOR-273903
NEK7phosphorylation

up-regulates activity
KIF14SIGNOR-266420
NEK7phosphorylation

up-regulates activity
KIF14SIGNOR-266419
NEK7phosphorylation

up-regulates activity
KIF14SIGNOR-266418
NEK7phosphorylation

up-regulates activity
KIF14SIGNOR-266416
NEK7phosphorylation

up-regulates activity
KIF14SIGNOR-266417
NEK7phosphorylation

down-regulates activity
EML4SIGNOR-279237
NEK7phosphorylation

up-regulates activity
EML4SIGNOR-273884