| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | DTD1 | Thr187 | ESSKERNtPRKEDRS | phosphorylation up-regulates activity | 25258324 | SIGNOR-273975 |
| CDC7 | DTD1 | Thr187 | ESSKERNtPRKEDRS | phosphorylation up-regulates activity | 25258324 | SIGNOR-273964 |
| CDC7 | DTD1 | Ser196 | RKEDRSAsSGAEGDV | phosphorylation up-regulates activity | 25258324 | SIGNOR-273962 |
| CSNK2A1 | DTD1 | Ser179 | KTRAKGPsESSKERN | phosphorylation up-regulates activity | 25258324 | SIGNOR-273979 |
| CSNK2A1 | DTD1 | Ser196 | RKEDRSAsSGAEGDV | phosphorylation up-regulates activity | 25258324 | SIGNOR-273971 |
| CSNK2A1 | DTD1 | Ser181 | RAKGPSEsSKERNTP | phosphorylation up-regulates activity | 25258324 | SIGNOR-273977 |
| CDC7 | DTD1 | Ser182 | AKGPSESsKERNTPR | phosphorylation up-regulates activity | 25258324 | SIGNOR-273967 |
| CSNK2A1 | DTD1 | Ser194 | TPRKEDRsASSGAEG | phosphorylation up-regulates activity | 25258324 | SIGNOR-273970 |
| CDC7 | DTD1 | Ser194 | TPRKEDRsASSGAEG | phosphorylation up-regulates activity | 25258324 | SIGNOR-273961 |
| CDC7 | DTD1 | Ser204 | SGAEGDVsSEREP | phosphorylation up-regulates activity | 25258324 | SIGNOR-273965 |
| CDC7 | DTD1 | Ser205 | GAEGDVSsEREP | phosphorylation up-regulates activity | 25258324 | SIGNOR-273969 |
| CDC7 | DTD1 | Ser179 | KTRAKGPsESSKERN | phosphorylation up-regulates activity | 25258324 | SIGNOR-273968 |
| CSNK2A1 | DTD1 | Ser205 | GAEGDVSsEREP | phosphorylation up-regulates activity | 25258324 | SIGNOR-273980 |
| CDC7 | DTD1 | Ser197 | KEDRSASsGAEGDVS | phosphorylation up-regulates activity | 25258324 | SIGNOR-273963 |
| CSNK2A1 | DTD1 | Ser197 | KEDRSASsGAEGDVS | phosphorylation up-regulates activity | 25258324 | SIGNOR-273972 |
| CSNK2A1 | DTD1 | Ser182 | AKGPSESsKERNTPR | phosphorylation up-regulates activity | 25258324 | SIGNOR-273978 |
| CDC7 | DTD1 | Ser181 | RAKGPSEsSKERNTP | phosphorylation up-regulates activity | 25258324 | SIGNOR-273966 |
| CSNK2A1 | DTD1 | Ser204 | SGAEGDVsSEREP | phosphorylation up-regulates activity | 25258324 | SIGNOR-273976 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PThr187 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273975 |
| CDC7 | phosphorylation up-regulates → | DTD1 PThr187 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273964 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer196 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273962 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer179 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273979 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer196 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273971 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer181 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273977 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer182 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273967 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer194 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273970 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer194 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273961 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer204 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273965 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer205 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273969 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer179 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273968 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer205 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273980 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer197 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273963 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer197 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273972 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer182 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273978 |
| CDC7 | phosphorylation up-regulates → | DTD1 PSer181 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273966 |
| CSNK2A1 | phosphorylation up-regulates → | DTD1 PSer204 | phosphorylation up-regulates → | DTD1 | 25258324 | SIGNOR-273976 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273975 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273964 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273962 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273979 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273971 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273977 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273967 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273970 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273961 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273965 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273969 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273968 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273980 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273963 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273972 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273978 |
| CDC7 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273966 |
| CSNK2A1 | phosphorylation → up-regulates activity | DTD1 | SIGNOR-273976 |
