| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKA | GRK7 | Ser23 | YLQARKPsDCDSKEL | phosphorylation down-regulates activity | 15946941 | SIGNOR-274081 |
| PKA | GRK7 | Ser23 | YLQARKPsDCDSKEL | phosphorylation down-regulates activity | 15946941 | SIGNOR-276036 |
| PKA | GRK7 | Ser23 | YLQARKPsDCDSKEL | phosphorylation down-regulates activity | 15946941 | SIGNOR-260839 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKA | phosphorylation up-regulates → | GRK7 PSer23 | phosphorylation down-regulates ⊣ | GRK7 | 15946941 | SIGNOR-274081 |
| PKA | phosphorylation up-regulates → | GRK7 PSer23 | phosphorylation down-regulates ⊣ | GRK7 | 15946941 | SIGNOR-276036 |
| PKA | phosphorylation up-regulates → | GRK7 PSer23 | phosphorylation down-regulates ⊣ | GRK7 | 15946941 | SIGNOR-260839 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKA | phosphorylation → down-regulates activity | GRK7 | SIGNOR-274081 |
| PKA | phosphorylation → down-regulates activity | GRK7 | SIGNOR-276036 |
| PKA | phosphorylation → down-regulates activity | GRK7 | SIGNOR-260839 |