| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | BLNK | Tyr84 | EHSDSEMyVMPAEEN | phosphorylation up-regulates | 12456653 | SIGNOR-96048 |
| PTPRG | BLNK | Tyr84 | EHSDSEMyVMPAEEN | dephosphorylation up-regulates activity | 25624455 | SIGNOR-254692 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | phosphorylation up-regulates → | BLNK PTyr84 | phosphorylation up-regulates → | BLNK | 12456653 | SIGNOR-96048 |
| PTPRG | dephosphorylation down-regulates ⊣ | BLNK PTyr84 | dephosphorylation down-regulates ⊣ | BLNK | 25624455 | SIGNOR-254692 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SYK | phosphorylation → up-regulates | BLNK | SIGNOR-96048 |
| PTPRG | dephosphorylation → up-regulates activity | BLNK | SIGNOR-254692 |
