| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | CKAP2 | Thr623 | FKELKFLtPVRRSRR | phosphorylation up-regulates | 19369249 | SIGNOR-216829 |
| CDK1 | CKAP2 | Thr623 | FKELKFLtPVRRSRR | phosphorylation up-regulates | 19369249 | SIGNOR-185317 |
| AURKB | CKAP2 | Ser628 | FLTPVRRsRRLQEKT | phosphorylation up-regulates | 20458174 | SIGNOR-165410 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | CKAP2 PThr623 | phosphorylation up-regulates → | CKAP2 | 19369249 | SIGNOR-216829 |
| CDK1 | phosphorylation up-regulates → | CKAP2 PThr623 | phosphorylation up-regulates → | CKAP2 | 19369249 | SIGNOR-185317 |
| AURKB | phosphorylation up-regulates → | CKAP2 PSer628 | phosphorylation up-regulates → | CKAP2 | 20458174 | SIGNOR-165410 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → up-regulates | CKAP2 | SIGNOR-216829 |
| CDK1 | phosphorylation → up-regulates | CKAP2 | SIGNOR-185317 |
| AURKB | phosphorylation → up-regulates | CKAP2 | SIGNOR-165410 |
