| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | ATRIP | Ser224 | APSVSHVsPRKNPSV | phosphorylation up-regulates | 17638878 | SIGNOR-156928 |
| ATR | ATRIP | Ser68 | EELDTLAsQALSQCP | phosphorylation up-regulates | 15451423 | SIGNOR-129469 |
| CDK2 | ATRIP | Ser239 | VIKPEACsPQFGKTS | phosphorylation unknown | 17638878 | SIGNOR-156932 |
| ATR | ATRIP | Ser72 | TLASQALsQCPAAAR | phosphorylation up-regulates | 15451423 | SIGNOR-129473 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | ATRIP PSer224 | phosphorylation up-regulates → | ATRIP | 17638878 | SIGNOR-156928 |
| ATR | phosphorylation up-regulates → | ATRIP PSer68 | phosphorylation up-regulates → | ATRIP | 15451423 | SIGNOR-129469 |
| CDK2 | phosphorylation up-regulates → | ATRIP PSer239 | phosphorylation down-regulates ⊣ | ATRIP | 17638878 | SIGNOR-156932 |
| ATR | phosphorylation up-regulates → | ATRIP PSer72 | phosphorylation up-regulates → | ATRIP | 15451423 | SIGNOR-129473 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation → up-regulates | ATRIP | SIGNOR-156928 |
| ATR | phosphorylation → up-regulates | ATRIP | SIGNOR-129469 |
| CDK2 | phosphorylation → unknown | ATRIP | SIGNOR-156932 |
| ATR | phosphorylation → up-regulates | ATRIP | SIGNOR-129473 |
