| Name | SSH1 |
| ID | Q8WYL5 |
| Role | phosphatase |
| Enzymatic Domains |
DEK-C 249-304 PROSITE-ProRule
Tyrosine-protein phosphatase 308-449 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SSH1 | CFL1 | Ser3 | sGVAVSDG | dephosphorylation up-regulates activity | 14531860 | SIGNOR-248762 |
| SSH1 | LIMK1 | – | dephosphorylation down-regulates activity | 23153585 | SIGNOR-277096 | |
| SSH1 | CORO1B | Ser2 | sFRKVVRQ | dephosphorylation up-regulates | 17350576 | SIGNOR-153604 |
| SSH1 | CORO1B | Ser2 | sFRKVVRQ | dephosphorylation up-regulates activity | 17350576 | SIGNOR-248763 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SSH1 | dephosphorylation down-regulates ⊣ | CFL1 PSer3 | dephosphorylation down-regulates ⊣ | CFL1 | 14531860 | SIGNOR-248762 |
| SSH1 | dephosphorylation down-regulates ⊣ | CORO1B PSer2 | dephosphorylation down-regulates ⊣ | CORO1B | 17350576 | SIGNOR-153604 |
| SSH1 | dephosphorylation down-regulates ⊣ | CORO1B PSer2 | dephosphorylation down-regulates ⊣ | CORO1B | 17350576 | SIGNOR-248763 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SSH1 | dephosphorylation → up-regulates activity | CFL1 | SIGNOR-248762 |
| SSH1 | dephosphorylation → down-regulates activity | LIMK1 | SIGNOR-277096 |
| SSH1 | dephosphorylation → up-regulates | CORO1B | SIGNOR-153604 |
| SSH1 | dephosphorylation → up-regulates activity | CORO1B | SIGNOR-248763 |