| Name | SSH1 |
| ID | Q8WYL5 |
| Role | substrate |
| Enzymatic Domains |
DEK-C 249-304 PROSITE-ProRule
Tyrosine-protein phosphatase 308-449 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | SSH1 | Ser937 | SNLTRSSsSDSIHSV | phosphorylation down-regulates | 21525957 | SIGNOR-173437 |
| PRKD2 | SSH1 | Ser978 | SPLKRSHsLAKLGSL | phosphorylation down-regulates activity | 21832093 | SIGNOR-275937 |
| PRKD1 | SSH1 | Ser937 | SNLTRSSsSDSIHSV | phosphorylation down-regulates | 19567672 | SIGNOR-186467 |
| PRKD3 | SSH1 | Ser978 | SPLKRSHsLAKLGSL | phosphorylation down-regulates activity | 21832093 | SIGNOR-275938 |
| PRKD1 | SSH1 | Ser978 | SPLKRSHsLAKLGSL | phosphorylation down-regulates activity | 21832093 | SIGNOR-275936 |
| PRKD1 | SSH1 | Ser978 | SPLKRSHsLAKLGSL | phosphorylation down-regulates | 19567672 | SIGNOR-186471 |
| PRKD2 | SSH1 | Ser937 | SNLTRSSsSDSIHSV | phosphorylation down-regulates | 21525957 | SIGNOR-173441 |
| PRKD1 | SSH1 | Ser99 | KLAVRLEsAWADRVR | phosphorylation up-regulates activity | 23841590 | SIGNOR-275939 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | phosphorylation up-regulates → | SSH1 PSer937 | phosphorylation down-regulates ⊣ | SSH1 | 21525957 | SIGNOR-173437 |
| PRKD2 | phosphorylation up-regulates → | SSH1 PSer978 | phosphorylation down-regulates ⊣ | SSH1 | 21832093 | SIGNOR-275937 |
| PRKD1 | phosphorylation up-regulates → | SSH1 PSer937 | phosphorylation down-regulates ⊣ | SSH1 | 19567672 | SIGNOR-186467 |
| PRKD3 | phosphorylation up-regulates → | SSH1 PSer978 | phosphorylation down-regulates ⊣ | SSH1 | 21832093 | SIGNOR-275938 |
| PRKD1 | phosphorylation up-regulates → | SSH1 PSer978 | phosphorylation down-regulates ⊣ | SSH1 | 21832093 | SIGNOR-275936 |
| PRKD1 | phosphorylation up-regulates → | SSH1 PSer978 | phosphorylation down-regulates ⊣ | SSH1 | 19567672 | SIGNOR-186471 |
| PRKD2 | phosphorylation up-regulates → | SSH1 PSer937 | phosphorylation down-regulates ⊣ | SSH1 | 21525957 | SIGNOR-173441 |
| PRKD1 | phosphorylation up-regulates → | SSH1 PSer99 | phosphorylation up-regulates → | SSH1 | 23841590 | SIGNOR-275939 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKD1 | phosphorylation down-regulates | SSH1 | SIGNOR-173437 |
| PRKD2 | phosphorylation → down-regulates activity | SSH1 | SIGNOR-275937 |
| PRKD1 | phosphorylation down-regulates | SSH1 | SIGNOR-186467 |
| PRKD3 | phosphorylation → down-regulates activity | SSH1 | SIGNOR-275938 |
| PRKD1 | phosphorylation → down-regulates activity | SSH1 | SIGNOR-275936 |
| PRKD1 | phosphorylation down-regulates | SSH1 | SIGNOR-186471 |
| PRKD2 | phosphorylation down-regulates | SSH1 | SIGNOR-173441 |
| PRKD1 | phosphorylation → up-regulates activity | SSH1 | SIGNOR-275939 |