Entity Details

Name NTRK1_Tyr219
ID Q92529-2
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCSHC3Tyr219DGSDHPYyNSIPSKMphosphorylation
up-regulates activity		11791173SIGNOR-273921
NTRK2SHC3Tyr219DGSDHPYyNSIPSKMphosphorylation
up-regulates activity		11791173SIGNOR-273918
EGFRSHC3Tyr219DGSDHPYyNSIPSKMphosphorylation
up-regulates activity		11791173SIGNOR-273912
NTRK1SHC3Tyr219DGSDHPYyNSIPSKMphosphorylation
up-regulates activity		11791173SIGNOR-273915
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
SHC3
PTyr219		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273921
NTRK2phosphorylation
up-regulates
→
SHC3
PTyr219		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273918
EGFRphosphorylation
up-regulates
→
SHC3
PTyr219		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273912
NTRK1phosphorylation
up-regulates
→
SHC3
PTyr219		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273915
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		SHC3SIGNOR-273921
NTRK2phosphorylation
→
up-regulates activity 		SHC3SIGNOR-273918
EGFRphosphorylation
→
up-regulates activity 		SHC3SIGNOR-273912
NTRK1phosphorylation
→
up-regulates activity 		SHC3SIGNOR-273915