Entity Details

Name NTRK1_Tyr301
ID Q92529-2
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCSHC3Tyr301PTGEAPTyVNTQQIPphosphorylation
up-regulates activity		11791173SIGNOR-273925
NTRK2SHC3Tyr301PTGEAPTyVNTQQIPphosphorylation
up-regulates activity		11791173SIGNOR-273924
EGFRSHC3Tyr301PTGEAPTyVNTQQIPphosphorylation
up-regulates activity		11791173SIGNOR-273922
NTRK1SHC3Tyr301PTGEAPTyVNTQQIPphosphorylation
up-regulates activity		11791173SIGNOR-273923
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
SHC3
PTyr301		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273925
NTRK2phosphorylation
up-regulates
→
SHC3
PTyr301		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273924
EGFRphosphorylation
up-regulates
→
SHC3
PTyr301		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273922
NTRK1phosphorylation
up-regulates
→
SHC3
PTyr301		phosphorylation
up-regulates
→		SHC311791173SIGNOR-273923
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		SHC3SIGNOR-273925
NTRK2phosphorylation
→
up-regulates activity 		SHC3SIGNOR-273924
EGFRphosphorylation
→
up-regulates activity 		SHC3SIGNOR-273922
NTRK1phosphorylation
→
up-regulates activity 		SHC3SIGNOR-273923