Entity Details

Name NDRG1
ID Q92597
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PIM1NDRG1Ser330 LMRSRTAsGSSVTSLphosphorylation
down-regulates activity
33398037SIGNOR-279308
SGK1NDRG1Ser330 LMRSRTAsGSSVTSLphosphorylation
down-regulates
20416281SIGNOR-164898
SGK1NDRG1Thr346 GTRSRSHtSEGTRSRphosphorylation
up-regulates
18787837SIGNOR-180821
SGK1NDRG1Thr356GTRSRSHtSEGTRSRphosphorylation
up-regulates
18787837SIGNOR-180825
SGK3NDRG1–phosphorylation
down-regulates activity
25458846SIGNOR-279282
SGK1NDRG1Thr366 GTRSRSHtSEGAHLDphosphorylation
up-regulates
18787837SIGNOR-180829
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PIM1phosphorylation
up-regulates
→
NDRG1
PSer330
phosphorylation
down-regulates
⊣
NDRG133398037SIGNOR-279308
SGK1phosphorylation
up-regulates
→
NDRG1
PSer330
phosphorylation
down-regulates
⊣
NDRG120416281SIGNOR-164898
SGK1phosphorylation
up-regulates
→
NDRG1
PThr346
phosphorylation
up-regulates
→
NDRG118787837SIGNOR-180821
SGK1phosphorylation
up-regulates
→
NDRG1
PThr356
phosphorylation
up-regulates
→
NDRG118787837SIGNOR-180825
SGK1phosphorylation
up-regulates
→
NDRG1
PThr366
phosphorylation
up-regulates
→
NDRG118787837SIGNOR-180829
Regulator Mechanism/Effect Target SIGNOR-ID
PIM1phosphorylation
→
down-regulates activity
NDRG1SIGNOR-279308
SGK1phosphorylation
img/direct_inhibition.png
down-regulates
NDRG1SIGNOR-164898
SGK1phosphorylation
→
up-regulates
NDRG1SIGNOR-180821
SGK1phosphorylation
→
up-regulates
NDRG1SIGNOR-180825
SGK3phosphorylation
→
down-regulates activity
NDRG1SIGNOR-279282
SGK1phosphorylation
→
up-regulates
NDRG1SIGNOR-180829