| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PIM1 | NDRG1 | Ser330 | LMRSRTAsGSSVTSL | phosphorylation down-regulates activity | 33398037 | SIGNOR-279308 |
| SGK1 | NDRG1 | Ser330 | LMRSRTAsGSSVTSL | phosphorylation down-regulates | 20416281 | SIGNOR-164898 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PIM1 | phosphorylation up-regulates → | NDRG1 PSer330 | phosphorylation down-regulates ⊣ | NDRG1 | 33398037 | SIGNOR-279308 |
| SGK1 | phosphorylation up-regulates → | NDRG1 PSer330 | phosphorylation down-regulates ⊣ | NDRG1 | 20416281 | SIGNOR-164898 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PIM1 | phosphorylation → down-regulates activity | NDRG1 | SIGNOR-279308 |
| SGK1 | phosphorylation down-regulates | NDRG1 | SIGNOR-164898 |
