Entity Details

Name PRKACA_Ser188
ID Q92837
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKACAFRAT1Ser188RLQQRRGsQPETRTGphosphorylation
down-regulates		16982607SIGNOR-149689
GSK3BFRAT1Ser188RLQQRRGsQPETRTGphosphorylation
down-regulates activity		16982607SIGNOR-276057
PKAFRAT1Ser188RLQQRRGsQPETRTGphosphorylation
down-regulates activity		16982607SIGNOR-276058
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKACAphosphorylation
up-regulates
→
FRAT1
PSer188		phosphorylation
down-regulates
⊣		FRAT116982607SIGNOR-149689
GSK3Bphosphorylation
up-regulates
→
FRAT1
PSer188		phosphorylation
down-regulates
⊣		FRAT116982607SIGNOR-276057
PKAphosphorylation
up-regulates
→
FRAT1
PSer188		phosphorylation
down-regulates
⊣		FRAT116982607SIGNOR-276058
Regulator Mechanism/Effect Target SIGNOR-ID
PRKACAphosphorylation
img/direct_inhibition.png
down-regulates 		FRAT1SIGNOR-149689
GSK3Bphosphorylation
→
down-regulates activity 		FRAT1SIGNOR-276057
PKAphosphorylation
→
down-regulates activity 		FRAT1SIGNOR-276058