| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKE | TANK | Ser409 | VFPPSITsRGDFLRH | phosphorylation down-regulates activity | 10759890 | SIGNOR-262721 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKE | phosphorylation up-regulates → | TANK PSer409 | phosphorylation down-regulates ⊣ | TANK | 10759890 | SIGNOR-262721 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IKBKE | phosphorylation → down-regulates activity | TANK | SIGNOR-262721 |