| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKB | COPS5 | Thr205 | EGPSEYQtIPLNKIE | phosphorylation down-regulates activity | 31950832 | SIGNOR-275519 |
| CHUK | COPS5 | Thr205 | EGPSEYQtIPLNKIE | phosphorylation down-regulates activity | 31950832 | SIGNOR-275508 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKB | phosphorylation up-regulates → | COPS5 PThr205 | phosphorylation down-regulates ⊣ | COPS5 | 31950832 | SIGNOR-275519 |
| CHUK | phosphorylation up-regulates → | COPS5 PThr205 | phosphorylation down-regulates ⊣ | COPS5 | 31950832 | SIGNOR-275508 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IKBKB | phosphorylation → down-regulates activity | COPS5 | SIGNOR-275519 |
| CHUK | phosphorylation → down-regulates activity | COPS5 | SIGNOR-275508 |