| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | KHSRP | Ser193 | GLPERSVsLTGAPES | phosphorylation down-regulates activity | 17177604 | SIGNOR-252497 |
| AKT | KHSRP | Ser193 | GLPERSVsLTGAPES | phosphorylation down-regulates activity | 17177604 | SIGNOR-151216 |
| AKT2 | KHSRP | Ser193 | GLPERSVsLTGAPES | phosphorylation down-regulates | 17177604 | SIGNOR-151220 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | KHSRP PSer193 | phosphorylation down-regulates ⊣ | KHSRP | 17177604 | SIGNOR-252497 |
| AKT | phosphorylation up-regulates → | KHSRP PSer193 | phosphorylation down-regulates ⊣ | KHSRP | 17177604 | SIGNOR-151216 |
| AKT2 | phosphorylation up-regulates → | KHSRP PSer193 | phosphorylation down-regulates ⊣ | KHSRP | 17177604 | SIGNOR-151220 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → down-regulates activity | KHSRP | SIGNOR-252497 |
| AKT | phosphorylation → down-regulates activity | KHSRP | SIGNOR-151216 |
| AKT2 | phosphorylation![]() down-regulates | KHSRP | SIGNOR-151220 |