Entity Details

Name KAT5
ID Q92993
Role substrate
Enzymatic Domains
Tudor-knot 8-65

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MYST-type HAT 227-504
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCEKAT5–phosphorylation
up-regulates activity		17851107SIGNOR-279309
GSK3BKAT5Ser86
View in OncoXplorer
TKNGLPGsRPGSPERphosphorylation
up-regulates		21658600SIGNOR-174049
CDK1KAT5Ser86
View in OncoXplorer
TKNGLPGsRPGSPERphosphorylation
up-regulates		16103124SIGNOR-139649
CDK1KAT5Ser90
View in OncoXplorer
LPGSRPGsPEREVPAphosphorylation
up-regulates		16103124SIGNOR-139653
CyclinB/CDK1KAT5Ser90
View in OncoXplorer
LPGSRPGsPEREVPAphosphorylation
up-regulates activity		12468530SIGNOR-250642
CyclinB/CDK1KAT5Ser86
View in OncoXplorer
TKNGLPGsRPGSPERphosphorylation
up-regulates activity		12468530SIGNOR-250641
ABL1KAT5Tyr294HPPGNEIyRKGTISFphosphorylation
down-regulates activity		24044023SIGNOR-276598
MAPK14KAT5Thr158
View in OncoXplorer
VEVVSPAtPVPSETAphosphorylation
up-regulates activity		25544752SIGNOR-278958
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
KAT5
PSer86		phosphorylation
up-regulates
→		KAT521658600SIGNOR-174049
CDK1phosphorylation
up-regulates
→
KAT5
PSer86		phosphorylation
up-regulates
→		KAT516103124SIGNOR-139649
CDK1phosphorylation
up-regulates
→
KAT5
PSer90		phosphorylation
up-regulates
→		KAT516103124SIGNOR-139653
CyclinB/CDK1phosphorylation
up-regulates
→
KAT5
PSer90		phosphorylation
up-regulates
→		KAT512468530SIGNOR-250642
CyclinB/CDK1phosphorylation
up-regulates
→
KAT5
PSer86		phosphorylation
up-regulates
→		KAT512468530SIGNOR-250641
ABL1phosphorylation
up-regulates
→
KAT5
PTyr294		phosphorylation
down-regulates
⊣		KAT524044023SIGNOR-276598
MAPK14phosphorylation
up-regulates
→
KAT5
PThr158		phosphorylation
up-regulates
→		KAT525544752SIGNOR-278958
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCEphosphorylation
→
up-regulates activity 		KAT5SIGNOR-279309
GSK3Bphosphorylation
→
up-regulates 		KAT5SIGNOR-174049
CDK1phosphorylation
→
up-regulates 		KAT5SIGNOR-139649
CDK1phosphorylation
→
up-regulates 		KAT5SIGNOR-139653
CyclinB/CDK1phosphorylation
→
up-regulates activity 		KAT5SIGNOR-250642
CyclinB/CDK1phosphorylation
→
up-regulates activity 		KAT5SIGNOR-250641
ABL1phosphorylation
→
down-regulates activity 		KAT5SIGNOR-276598
MAPK14phosphorylation
→
up-regulates activity 		KAT5SIGNOR-278958