| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | KAT5 | Ser86 | TKNGLPGsRPGSPER | phosphorylation up-regulates activity | 12468530 | SIGNOR-250641 |
| GSK3B | KAT5 | Ser86 | TKNGLPGsRPGSPER | phosphorylation up-regulates | 21658600 | SIGNOR-174049 |
| CDK1 | KAT5 | Ser86 | TKNGLPGsRPGSPER | phosphorylation up-regulates | 16103124 | SIGNOR-139649 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | KAT5 PSer86 | phosphorylation up-regulates → | KAT5 | 12468530 | SIGNOR-250641 |
| GSK3B | phosphorylation up-regulates → | KAT5 PSer86 | phosphorylation up-regulates → | KAT5 | 21658600 | SIGNOR-174049 |
| CDK1 | phosphorylation up-regulates → | KAT5 PSer86 | phosphorylation up-regulates → | KAT5 | 16103124 | SIGNOR-139649 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → up-regulates activity | KAT5 | SIGNOR-250641 |
| GSK3B | phosphorylation → up-regulates | KAT5 | SIGNOR-174049 |
| CDK1 | phosphorylation → up-regulates | KAT5 | SIGNOR-139649 |
