Entity Details

Name CDK1_Ser2547
ID Q93008
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1USP9XSer2547YEGSEEVsPPQTKDQphosphorylation
up-regulates activity		32152317SIGNOR-275608
CDC14BUSP9XSer2547YEGSEEVsPPQTKDQdephosphorylation
down-regulates quantity by destabilization		32152317SIGNOR-275613
CyclinB/CDK1USP9XSer2547YEGSEEVsPPQTKDQphosphorylation
up-regulates activity		32152317SIGNOR-275612
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
USP9X
PSer2547		phosphorylation
up-regulates
→		USP9X32152317SIGNOR-275608
CDC14Bdephosphorylation
down-regulates
⊣
USP9X
PSer2547		dephosphorylation
up-regulates
→		USP9X32152317SIGNOR-275613
CyclinB/CDK1phosphorylation
up-regulates
→
USP9X
PSer2547		phosphorylation
up-regulates
→		USP9X32152317SIGNOR-275612
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
up-regulates activity 		USP9XSIGNOR-275608
CDC14Bdephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		USP9XSIGNOR-275613
CyclinB/CDK1phosphorylation
→
up-regulates activity 		USP9XSIGNOR-275612