| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK2 | FBXW7 | Ser176 | KRKLDHGsEVRSFSL | phosphorylation down-regulates | 22399798 | SIGNOR-196448 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK2 | phosphorylation up-regulates → | FBXW7 PSer176 | phosphorylation down-regulates ⊣ | FBXW7 | 22399798 | SIGNOR-196448 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK2 | phosphorylation![]() down-regulates | FBXW7 | SIGNOR-196448 |