| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-123226 |
| PRKCA | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-96692 |
| ILK | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 12144526 | SIGNOR-90828 |
| PRKD1 | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-249260 |
| ROCK2 | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-90832 |
| ROCK2 | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-96696 |
| PRKCE | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-249258 |
| PRKCA | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-249259 |
| PRKCZ | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-249261 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-123226 |
| PRKCA | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-96692 |
| ILK | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 12144526 | SIGNOR-90828 |
| PRKD1 | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-249260 |
| ROCK2 | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-90832 |
| ROCK2 | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-96696 |
| PRKCE | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-249258 |
| PRKCA | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-249259 |
| PRKCZ | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-249261 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKD1 | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-123226 |
| PRKCA | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-96692 |
| ILK | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-90828 |
| PRKD1 | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-249260 |
| ROCK2 | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-90832 |
| ROCK2 | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-96696 |
| PRKCE | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-249258 |
| PRKCA | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-249259 |
| PRKCZ | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-249261 |
