| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TBK1 | PBXIP1 | Ser147 | REEGRCSsSDDDTDV | phosphorylation down-regulates quantity by destabilization | 24488098 | SIGNOR-273811 |
| TBK1 | PBXIP1 | Ser147 | REEGRCSsSDDDTDV | phosphorylation down-regulates quantity by destabilization | 24488098 | SIGNOR-273643 |
| IKBKE | PBXIP1 | Ser147 | REEGRCSsSDDDTDV | phosphorylation down-regulates quantity by destabilization | 24488098 | SIGNOR-276618 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TBK1 | phosphorylation up-regulates → | PBXIP1 PSer147 | phosphorylation down-regulates ⊣ | PBXIP1 | 24488098 | SIGNOR-273811 |
| TBK1 | phosphorylation up-regulates → | PBXIP1 PSer147 | phosphorylation down-regulates ⊣ | PBXIP1 | 24488098 | SIGNOR-273643 |
| IKBKE | phosphorylation up-regulates → | PBXIP1 PSer147 | phosphorylation down-regulates ⊣ | PBXIP1 | 24488098 | SIGNOR-276618 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| TBK1 | phosphorylation![]() down-regulates quantity by destabilization | PBXIP1 | SIGNOR-273811 |
| TBK1 | phosphorylation![]() down-regulates quantity by destabilization | PBXIP1 | SIGNOR-273643 |
| IKBKE | phosphorylation![]() down-regulates quantity by destabilization | PBXIP1 | SIGNOR-276618 |