| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | AKT1S1 | Ser212 | EENGPPSsPDLDRIA | phosphorylation down-regulates activity | 18372248 | SIGNOR-178124 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | phosphorylation up-regulates → | AKT1S1 PSer212 | phosphorylation down-regulates ⊣ | AKT1S1 | 18372248 | SIGNOR-178124 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MTOR | phosphorylation → down-regulates activity | AKT1S1 | SIGNOR-178124 |
