Entity Details

Name AKT1_Thr246
ID Q96B36
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1AKT1S1Thr246LPRPRLNtSDFQKLKphosphorylation
down-regulates activity		12524439SIGNOR-252544
AKT2AKT1S1Thr246LPRPRLNtSDFQKLKphosphorylation
down-regulates activity		12524439SIGNOR-248046
DYRK3AKT1S1Thr246LPRPRLNtSDFQKLKphosphorylation
down-regulates activity		23415227SIGNOR-279167
AKTAKT1S1Thr246LPRPRLNtSDFQKLKphosphorylation
down-regulates activity		12524439SIGNOR-236929
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
AKT1S1
PThr246		phosphorylation
down-regulates
⊣		AKT1S112524439SIGNOR-252544
AKT2phosphorylation
up-regulates
→
AKT1S1
PThr246		phosphorylation
down-regulates
⊣		AKT1S112524439SIGNOR-248046
DYRK3phosphorylation
up-regulates
→
AKT1S1
PThr246		phosphorylation
down-regulates
⊣		AKT1S123415227SIGNOR-279167
AKTphosphorylation
up-regulates
→
AKT1S1
PThr246		phosphorylation
down-regulates
⊣		AKT1S112524439SIGNOR-236929
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
down-regulates activity 		AKT1S1SIGNOR-252544
AKT2phosphorylation
→
down-regulates activity 		AKT1S1SIGNOR-248046
DYRK3phosphorylation
→
down-regulates activity 		AKT1S1SIGNOR-279167
AKTphosphorylation
→
down-regulates activity 		AKT1S1SIGNOR-236929