| Name | PINX1 |
| ID | Q96BK5 |
| Role | substrate |
| Enzymatic Domains |
G-patch 26-72 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | PINX1 | Thr317 | EDATLEEtLVKKKKK | phosphorylation down-regulates | 20573420 | SIGNOR-166333 |
| PLK1 | PINX1 | Ser110 | SDKKEKKsFSLEEKS | phosphorylation down-regulates | 20573420 | SIGNOR-166317 |
| PLK1 | PINX1 | Ser226 | ATGKDVEsYLQPKAK | phosphorylation down-regulates | 20573420 | SIGNOR-166325 |
| PLK1 | PINX1 | Thr141 | DLSSRSKtDLDCIFG | phosphorylation down-regulates | 20573420 | SIGNOR-166329 |
| PLK1 | PINX1 | Ser117 | SFSLEEKsKISKNRV | phosphorylation down-regulates | 20573420 | SIGNOR-166321 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | PINX1 PThr317 | phosphorylation down-regulates ⊣ | PINX1 | 20573420 | SIGNOR-166333 |
| PLK1 | phosphorylation up-regulates → | PINX1 PSer110 | phosphorylation down-regulates ⊣ | PINX1 | 20573420 | SIGNOR-166317 |
| PLK1 | phosphorylation up-regulates → | PINX1 PSer226 | phosphorylation down-regulates ⊣ | PINX1 | 20573420 | SIGNOR-166325 |
| PLK1 | phosphorylation up-regulates → | PINX1 PThr141 | phosphorylation down-regulates ⊣ | PINX1 | 20573420 | SIGNOR-166329 |
| PLK1 | phosphorylation up-regulates → | PINX1 PSer117 | phosphorylation down-regulates ⊣ | PINX1 | 20573420 | SIGNOR-166321 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | phosphorylation down-regulates | PINX1 | SIGNOR-166333 |
| PLK1 | phosphorylation down-regulates | PINX1 | SIGNOR-166317 |
| PLK1 | phosphorylation down-regulates | PINX1 | SIGNOR-166325 |
| PLK1 | phosphorylation down-regulates | PINX1 | SIGNOR-166329 |
| PLK1 | phosphorylation down-regulates | PINX1 | SIGNOR-166321 |