| Name | SGK3 |
| ID | Q96BR1 |
| Role | substrate |
| Enzymatic Domains |
PX 12-124 PROSITE-ProRule
Protein kinase 162-419 PROSITE-ProRule
AGC-kinase C-terminal 420-496 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | SGK3 | – | phosphorylation up-regulates | 15209375 | SIGNOR-126236 | |
| PDPK1 | SGK3 | Ser486 | DDAFVGFsYAPPSED | phosphorylation up-regulates activity | 10548550 | SIGNOR-250278 |
| PDPK1 | SGK3 | Thr320 | AISDTTTtFCGTPEY | phosphorylation up-regulates | 16790420 | SIGNOR-147213 |
| PDPK1 | SGK3 | Thr320 | AISDTTTtFCGTPEY | phosphorylation up-regulates activity | 10548550 | SIGNOR-250279 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | phosphorylation up-regulates → | SGK3 PSer486 | phosphorylation up-regulates → | SGK3 | 10548550 | SIGNOR-250278 |
| PDPK1 | phosphorylation up-regulates → | SGK3 PThr320 | phosphorylation up-regulates → | SGK3 | 16790420 | SIGNOR-147213 |
| PDPK1 | phosphorylation up-regulates → | SGK3 PThr320 | phosphorylation up-regulates → | SGK3 | 10548550 | SIGNOR-250279 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PDPK1 | phosphorylation → up-regulates | SGK3 | SIGNOR-126236 |
| PDPK1 | phosphorylation → up-regulates activity | SGK3 | SIGNOR-250278 |
| PDPK1 | phosphorylation → up-regulates | SGK3 | SIGNOR-147213 |
| PDPK1 | phosphorylation → up-regulates activity | SGK3 | SIGNOR-250279 |