Entity Details

Name TIFA
ID Q96CG3
Role substrate
Enzymatic Domains
FHA 47-103
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ALPK1TIFAThr9TSFEDADtEETVTCLphosphorylation
up-regulates activity		30111836SIGNOR-273543
ALPK1TIFA–phosphorylation
up-regulates activity		30308148SIGNOR-279789
AURKATIFAThr9TSFEDADtEETVTCLphosphorylation
up-regulates activity		28069801SIGNOR-273551
AKT1TIFAThr9TSFEDADtEETVTCLphosphorylation
up-regulates activity		27965388SIGNOR-273542
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ALPK1phosphorylation
up-regulates
→
TIFA
PThr9		phosphorylation
up-regulates
→		TIFA30111836SIGNOR-273543
AURKAphosphorylation
up-regulates
→
TIFA
PThr9		phosphorylation
up-regulates
→		TIFA28069801SIGNOR-273551
AKT1phosphorylation
up-regulates
→
TIFA
PThr9		phosphorylation
up-regulates
→		TIFA27965388SIGNOR-273542
Regulator Mechanism/Effect Target SIGNOR-ID
ALPK1phosphorylation
→
up-regulates activity 		TIFASIGNOR-273543
ALPK1phosphorylation
→
up-regulates activity 		TIFASIGNOR-279789
AURKAphosphorylation
→
up-regulates activity 		TIFASIGNOR-273551
AKT1phosphorylation
→
up-regulates activity 		TIFASIGNOR-273542