| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | IL17RA | Thr780 | MVLTDPHtPYEEEQR | phosphorylation down-regulates quantity by destabilization | 26871944 | SIGNOR-277206 |
| GSK3B | IL17RA | Thr780 | MVLTDPHtPYEEEQR | phosphorylation down-regulates quantity by destabilization | 26871944 | SIGNOR-277205 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | phosphorylation up-regulates → | IL17RA PThr780 | phosphorylation down-regulates ⊣ | IL17RA | 26871944 | SIGNOR-277206 |
| GSK3B | phosphorylation up-regulates → | IL17RA PThr780 | phosphorylation down-regulates ⊣ | IL17RA | 26871944 | SIGNOR-277205 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3A | phosphorylation![]() down-regulates quantity by destabilization | IL17RA | SIGNOR-277206 |
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | IL17RA | SIGNOR-277205 |