| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDXP | CFL1 | Ser3 | sGVAVSDG | dephosphorylation down-regulates activity | 15580268 | SIGNOR-248764 |
| PDXP | MDM2 | Ser166 | SSRRRAIsETEENSD | dephosphorylation down-regulates activity | 33414453 | SIGNOR-277151 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDXP | dephosphorylation down-regulates ⊣ | CFL1 PSer3 | dephosphorylation up-regulates → | CFL1 | 15580268 | SIGNOR-248764 |
| PDXP | dephosphorylation down-regulates ⊣ | MDM2 PSer166 | dephosphorylation up-regulates → | MDM2 | 33414453 | SIGNOR-277151 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PDXP | dephosphorylation → down-regulates activity | CFL1 | SIGNOR-248764 |
| PDXP | dephosphorylation → down-regulates activity | MDM2 | SIGNOR-277151 |
