| Name | AURKB |
| ID | Q96GD4 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 77-327 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKB | ATM | Ser1403 | CHKTKLKsILEILSK | phosphorylation up-regulates | 22099307 | SIGNOR-177280 |
| AURKB | HDAC9 | Ser239 | QKVAERRsSPLLRRK | phosphorylation down-regulates | 22865920 | SIGNOR-198654 |
| AURKB | INCENP | Thr892 | KPRYHKRtSSAVWNS | phosphorylation up-regulates | 12925766 | SIGNOR-118019 |
| AURKB | NINL | Ser185 | WDSEDFGsPQKSCSP | phosphorylation up-regulates | 20864540 | SIGNOR-168045 |
| AURKB | CENPA | Ser7 | sRKPEAPR | phosphorylation unknown | 11756469 | SIGNOR-250585 |
| AURKB | CDC20 | – | phosphorylation down-regulates activity | 28434146 | SIGNOR-280190 | |
| AURKB | CDCA2 | Ser893 | SETKVRRsTRLQKDL | phosphorylation down-regulates activity | 23746640 | SIGNOR-280191 |
| AURKB | KIF23 | – | phosphorylation down-regulates quantity | 25512391 | SIGNOR-280192 | |
| AURKB | NDC80 | Ser44 | KPTFGKLsINKPTSE | phosphorylation down-regulates | 20471944 | SIGNOR-165558 |
| AURKB | DES | Thr17 | RVSSYRRtFGGAPGF | phosphorylation down-regulates | 12686604 | SIGNOR-100115 |
| AURKB | CKAP2 | Ser628 | FLTPVRRsRRLQEKT | phosphorylation up-regulates | 20458174 | SIGNOR-165410 |
| AURKB | NDC80 | Ser5 | sVSSGGAG | phosphorylation down-regulates | 20471944 | SIGNOR-165562 |
| AURKB | GFAP | Thr7 | tSAARRSY | phosphorylation down-regulates activity | 12686604 | SIGNOR-100173 |
| AURKB | PLK1 | Thr210 | YDGERKKtLCGTPNY | phosphorylation up-regulates activity | 26206521 | SIGNOR-279358 |
| AURKB | POU5F1 | – | phosphorylation down-regulates activity | 26880562 | SIGNOR-279592 | |
| AURKB | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 12686604 | SIGNOR-100169 |
| AURKB | ZWINT | Ser262 | MGRDPGVsFKAVGLQ | phosphorylation up-regulates activity | 21775627 | SIGNOR-265011 |
| AURKB | SKA1 | – | phosphorylation up-regulates activity | 22371557 | SIGNOR-262662 | |
| AURKB | CASP2 | Ser384 | MRNTKRGsWYIEALA | phosphorylation up-regulates activity | 32811973 | SIGNOR-279496 |
| AURKB | KIF2C | Ser192 | VNSVRRKsCLVKEVE | phosphorylation down-regulates | 17567953 | SIGNOR-155898 |
| AURKB | HDAC4 | Ser265 | QKVAERRsSPLLRRK | phosphorylation down-regulates | 22865920 | SIGNOR-198646 |
| AURKB | HASPIN | Ser108 | WKLRARPsLTVTPRR | phosphorylation up-regulates activity | 21658950 | SIGNOR-263137 |
| AURKB | BIRC5 | Thr117 | KNKIAKEtNNKKKEF | phosphorylation down-regulates | 17457057 | SIGNOR-154569 |
| AURKB | MAPRE3 | Ser176 | MQTSGRLsNVAPPCI | phosphorylation up-regulates | 23712260 | SIGNOR-202130 |
| AURKB | H3-3A | Ser11 | TKQTARKsTGGKAPR | phosphorylation up-regulates activity | 10464286 | SIGNOR-70420 |
| AURKB | WWC1 | Ser539 | TSLSPRSsLSSPSPP | phosphorylation unknown | 21878642 | SIGNOR-176363 |
| AURKB | CDCA8 | Ser275 | RLAQICSsIRTHK | phosphorylation up-regulates activity | 17483322 | SIGNOR-279506 |
| AURKB | HASPIN | Ser93 | RVPKDRPsLTVTPKR | phosphorylation up-regulates activity | 21658950 | SIGNOR-263139 |
| AURKB | SSU72 | Ser19 | CSSNQNRsMEAHNIL | phosphorylation down-regulates quantity by destabilization | 24149858 | SIGNOR-275529 |
| AURKB | CIT | – | phosphorylation down-regulates activity | 27009191 | SIGNOR-279140 | |
| AURKB | TP53 | Ser215 | DRNTFRHsVVVPYEP | phosphorylation down-regulates | 22611192 | SIGNOR-197602 |
| AURKB | NDC80 | Ser15 | SGGAGRLsMQELRSQ | phosphorylation down-regulates | 20471944 | SIGNOR-165554 |
| AURKB | CDCA5 | Ser126 | NPEAESSsKEGELDA | phosphorylation down-regulates activity | 23901111 | SIGNOR-276123 |
| AURKB | RACGAP1 | Ser187 | REKRRSTsRQFVDGP | phosphorylation up-regulates activity | 14744859 | SIGNOR-250588 |
| AURKB | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 12686604 | SIGNOR-100165 |
| AURKB | YY1 | Ser184 | GKKSGKKsYLSGGAG | phosphorylation up-regulates | 23226345 | SIGNOR-200079 |
| AURKB | KNL1 | Ser60 | KKNSRRVsFADTIKV | phosphorylation down-regulates | 20471944 | SIGNOR-165506 |
| AURKB | H3C1 | Ser29 | ATKAARKsAPATGGV | phosphorylation down-regulates activity | 21282660 | SIGNOR-171717 |
| AURKB | RPRD1B | Ser145 | KATEEKKsLKRTFQQ | phosphorylation up-regulates activity | 30518842 | SIGNOR-265499 |
| AURKB | CHMP4C | Ser214 | ARRSRAAsSQRAEEE | phosphorylation up-regulates | 22724069 | SIGNOR-197971 |
| AURKB | KNL1 | Ser24 | RPVRRRHsSILKPPR | phosphorylation down-regulates | 20471944 | SIGNOR-165502 |
| AURKB | NINL | Ser448 | QGYRERLsLLRSEVE | phosphorylation up-regulates | 20864540 | SIGNOR-168049 |
| AURKB | RACGAP1 | Thr186 | KREKRRStSRQFVDG | phosphorylation up-regulates activity | 14744859 | SIGNOR-250590 |
| AURKB | INCENP | Ser894 | RYHKRTSsAVWNSPP | phosphorylation up-regulates | 12925766 | SIGNOR-118015 |
| AURKB | CHMP4C | Ser215 | RRSRAASsQRAEEED | phosphorylation up-regulates | 22422861 | SIGNOR-196728 |
| AURKB | TP53 | Ser269 | GNLLGRNsFEVRVCA | phosphorylation down-regulates | 20959462 | SIGNOR-168745 |
| AURKB | CDCA2 | Ser542 | KKINRRKsQETKCTK | phosphorylation down-regulates activity | 32938714 | SIGNOR-274002 |
| AURKB | H3C1 | Ser11 | TKQTARKsTGGKAPR | phosphorylation up-regulates activity | 14583461 | SIGNOR-118894 |
| AURKB | HASPIN | Ser143 | PPFPSRDsGRLSPDL | phosphorylation up-regulates activity | 21658950 | SIGNOR-263138 |
| AURKB | ZWINT | Thr251 | TRPQEQStGDTMGRD | phosphorylation up-regulates activity | 21775627 | SIGNOR-265010 |
| AURKB | HASPIN | Ser93 | RVPKDRPsLTVTPKR | phosphorylation up-regulates activity | 21658950 | SIGNOR-262657 |
| AURKB | CHMP4C | Ser210 | MSSTARRsRAASSQR | phosphorylation up-regulates | 22724069 | SIGNOR-197967 |
| AURKB | CDCA2 | Ser977 | EPGKRRKsFCISTLA | phosphorylation down-regulates activity | 32938714 | SIGNOR-274004 |
| AURKB | H3-3A | Ser11 | TKQTARKsTGGKAPR | phosphorylation up-regulates activity | 12588998 | SIGNOR-98293 |
| AURKB | TERF1 | Ser404 | KYGEGNWsKILLHYK | phosphorylation up-regulates activity | 29040668 | SIGNOR-279440 |
| AURKB | ZWINT | Ser250 | PTRPQEQsTGDTMGR | phosphorylation up-regulates activity | 21775627 | SIGNOR-265009 |
| AURKB | KIF20A | Ser878 | RILRSRRsPLLKSGP | phosphorylation down-regulates activity | 27939310 | SIGNOR-262659 |
| AURKB | CDCA5 | Ser164 | TSTPGRRsCFGFEGL | phosphorylation down-regulates activity | 23901111 | SIGNOR-276113 |
| AURKB | YY1 | Ser180 | KKGGGKKsGKKSYLS | phosphorylation up-regulates | 23226345 | SIGNOR-200075 |
| AURKB | AURKB | Thr232 | APSLRRKtMCGTLDY | phosphorylation up-regulates | 14722118 | SIGNOR-121340 |
| AURKB | KIF4A | Thr799 | PPKLRRRtFSLTEVR | phosphorylation up-regulates activity | 28992084 | SIGNOR-265992 |
| AURKB | SSU72 | Ser19 | CSSNQNRsMEAHNIL | phosphorylation down-regulates activity | 24149858 | SIGNOR-275530 |
| AURKB | CDCA5 | Ser139 | DARDLEMsKKVRRSY | phosphorylation down-regulates activity | 23901111 | SIGNOR-276114 |
| AURKB | RACGAP1 | Ser144 | NAGNKRLsTIDESGS | phosphorylation up-regulates activity | 14744859 | SIGNOR-250586 |
| AURKB | DES | Ser12 | YSSSQRVsSYRRTFG | phosphorylation down-regulates | 12686604 | SIGNOR-100107 |
| AURKB | Histone H3 | – | phosphorylation up-regulates | 10464286 | SIGNOR-265321 | |
| AURKB | H3C1 | Ser29 | ATKAARKsAPATGGV | phosphorylation down-regulates activity | 11856369 | SIGNOR-114852 |
| AURKB | H1-4 | Ser27 | VKKKARKsAGAAKRK | phosphorylation up-regulates quantity by stabilization | 21511733 | SIGNOR-262658 |
| AURKB | RACGAP1 | Ser185 | KKREKRRsTSRQFVD | phosphorylation up-regulates activity | 14744859 | SIGNOR-250587 |
| AURKB | DIAPH2 | Ser196 | SLTSNPVsWVNNFGH | phosphorylation up-regulates | 21397845 | SIGNOR-172803 |
| AURKB | INCENP | Ser893 | PRYHKRTsSAVWNSP | phosphorylation up-regulates | 12925766 | SIGNOR-118011 |
| AURKB | VIM | Ser73 | SAVRLRSsVPGVRLL | phosphorylation down-regulates | 12458200 | SIGNOR-96057 |
| AURKB | TP53 | Thr211 | EYLDDRNtFRHSVVV | phosphorylation down-regulates | 22611192 | SIGNOR-197606 |
| AURKB | MYC | Ser67 | S-->K | phosphorylation up-regulates quantity by stabilization | 32049046 | SIGNOR-279439 |
| AURKB | RASSF1 | Ser207 | TSVRRRTsFYLPKDA | phosphorylation down-regulates | 19276349 | SIGNOR-184561 |
| AURKB | TP53BP1 | Ser1342 | GPLRGKTsGTEPADF | phosphorylation up-regulates activity | 28415769 | SIGNOR-264411 |
| AURKB | TP53 | Ser183 | CPHHERCsDSDGLAP | phosphorylation down-regulates | 22611192 | SIGNOR-197598 |
| AURKB | CDCA5 | Thr151 | RSYSRLEtLGSASTS | phosphorylation down-regulates activity | 23901111 | SIGNOR-276117 |
| AURKB | RACGAP1 | Thr145 | AGNKRLStIDESGSI | phosphorylation up-regulates activity | 14744859 | SIGNOR-250589 |
| AURKB | NINL | Ser585 | RLPKNRHsPSWSPDG | phosphorylation up-regulates | 20864540 | SIGNOR-168053 |
| AURKB | CDCA2 | Ser981 | RRKSFCIsTLANTKA | phosphorylation down-regulates activity | 32938714 | SIGNOR-274001 |
| AURKB | CDCA5 | Ser33 | LRRSQRKsGSELPSI | phosphorylation down-regulates activity | 23901111 | SIGNOR-276116 |
| AURKB | PLEKHG6 | Thr544 | SPSTRPStPSLEGSQ | phosphorylation up-regulates | 24482237 | SIGNOR-204534 |
| AURKB | DSN1 | Ser109 | KETNRRKsLHPIHQG | phosphorylation down-regulates | 20471944 | SIGNOR-165550 |
| AURKB | DSN1 | Ser100 | RQSWRRAsMKETNRR | phosphorylation down-regulates | 20471944 | SIGNOR-165546 |
| AURKB | H3C1 | Ser11 | TKQTARKsTGGKAPR | phosphorylation up-regulates activity | 12588998 | SIGNOR-98297 |
| AURKB | NSUN2 | Ser139 | SRKILRKsPHLEKFH | phosphorylation down-regulates | 17215513 | SIGNOR-152001 |
| AURKB | MAPRE2 | – | phosphorylation up-regulates activity | 27030108 | SIGNOR-279591 | |
| AURKB | KIF2C | Ser95 | IQKQKRRsVNSKIPA | phosphorylation up-regulates | 17567953 | SIGNOR-155890 |
| AURKB | SKA3 | Ser159 | SPRSPQLsDFGLERY | phosphorylation up-regulates activity | 22371557 | SIGNOR-262661 |
| AURKB | ARHGEF2 | Ser960 | SRLSPPHsPRDFTRM | phosphorylation down-regulates activity | 17488622 | SIGNOR-276062 |
| AURKB | SHCBP1 | Ser634 | QIKKKRLsELGITQA | phosphorylation up-regulates activity | 23704356 | SIGNOR-273552 |
| AURKB | HDAC5 | Ser278 | QKVAERRsSPLLRRK | phosphorylation down-regulates | 22865920 | SIGNOR-198650 |
| AURKB | TP53 | Thr284 | CPGRDRRtEEENLRK | phosphorylation down-regulates | 20959462 | SIGNOR-168749 |
| AURKB | H3-3A | Ser11 | TKQTARKsTGGKAPR | phosphorylation up-regulates activity | 14583461 | SIGNOR-118890 |
| AURKB | RACGAP1 | Ser387 | ETGLYRIsGCDRTVK | phosphorylation up-regulates activity | 12689593 | SIGNOR-100569 |
| AURKB | CDCA5 | Ser83 | PRRSPRIsFFLEKEN | phosphorylation down-regulates activity | 23901111 | SIGNOR-276119 |
| AURKB | DES | Ser60 | VYQVSRTsGGAGGLG | phosphorylation down-regulates | 12686604 | SIGNOR-100111 |
| AURKB | BUB1 | – | phosphorylation up-regulates activity | 34861183 | SIGNOR-279010 | |
| AURKB | MYBBP1A | Ser1303 | ARKKARLsLVIRSPS | phosphorylation unknown | 20177074 | SIGNOR-163903 |
| AURKB | KIF2C | Ser111 | KESLRSRsTRMSTVS | phosphorylation down-regulates | 17567953 | SIGNOR-155894 |
| AURKB | HASPIN | Ser143 | PPFPSRDsGRLSPDL | phosphorylation up-regulates activity | 21658950 | SIGNOR-262656 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKB | phosphorylation up-regulates → | ATM PSer1403 | phosphorylation up-regulates → | ATM | 22099307 | SIGNOR-177280 |
| AURKB | phosphorylation up-regulates → | HDAC9 PSer239 | phosphorylation down-regulates ⊣ | HDAC9 | 22865920 | SIGNOR-198654 |
| AURKB | phosphorylation up-regulates → | INCENP PThr892 | phosphorylation up-regulates → | INCENP | 12925766 | SIGNOR-118019 |
| AURKB | phosphorylation up-regulates → | NINL PSer185 | phosphorylation up-regulates → | NINL | 20864540 | SIGNOR-168045 |
| AURKB | phosphorylation up-regulates → | CENPA PSer7 | phosphorylation down-regulates ⊣ | CENPA | 11756469 | SIGNOR-250585 |
| AURKB | phosphorylation up-regulates → | CDCA2 PSer893 | phosphorylation down-regulates ⊣ | CDCA2 | 23746640 | SIGNOR-280191 |
| AURKB | phosphorylation up-regulates → | NDC80 PSer44 | phosphorylation down-regulates ⊣ | NDC80 | 20471944 | SIGNOR-165558 |
| AURKB | phosphorylation up-regulates → | DES PThr17 | phosphorylation down-regulates ⊣ | DES | 12686604 | SIGNOR-100115 |
| AURKB | phosphorylation up-regulates → | CKAP2 PSer628 | phosphorylation up-regulates → | CKAP2 | 20458174 | SIGNOR-165410 |
| AURKB | phosphorylation up-regulates → | NDC80 PSer5 | phosphorylation down-regulates ⊣ | NDC80 | 20471944 | SIGNOR-165562 |
| AURKB | phosphorylation up-regulates → | GFAP PThr7 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100173 |
| AURKB | phosphorylation up-regulates → | PLK1 PThr210 | phosphorylation up-regulates → | PLK1 | 26206521 | SIGNOR-279358 |
| AURKB | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100169 |
| AURKB | phosphorylation up-regulates → | ZWINT PSer262 | phosphorylation up-regulates → | ZWINT | 21775627 | SIGNOR-265011 |
| AURKB | phosphorylation up-regulates → | CASP2 PSer384 | phosphorylation up-regulates → | CASP2 | 32811973 | SIGNOR-279496 |
| AURKB | phosphorylation up-regulates → | KIF2C PSer192 | phosphorylation down-regulates ⊣ | KIF2C | 17567953 | SIGNOR-155898 |
| AURKB | phosphorylation up-regulates → | HDAC4 PSer265 | phosphorylation down-regulates ⊣ | HDAC4 | 22865920 | SIGNOR-198646 |
| AURKB | phosphorylation up-regulates → | HASPIN PSer108 | phosphorylation up-regulates → | HASPIN | 21658950 | SIGNOR-263137 |
| AURKB | phosphorylation up-regulates → | BIRC5 PThr117 | phosphorylation down-regulates ⊣ | BIRC5 | 17457057 | SIGNOR-154569 |
| AURKB | phosphorylation up-regulates → | MAPRE3 PSer176 | phosphorylation up-regulates → | MAPRE3 | 23712260 | SIGNOR-202130 |
| AURKB | phosphorylation up-regulates → | H3-3A PSer11 | phosphorylation up-regulates → | H3-3A | 10464286 | SIGNOR-70420 |
| AURKB | phosphorylation up-regulates → | WWC1 PSer539 | phosphorylation down-regulates ⊣ | WWC1 | 21878642 | SIGNOR-176363 |
| AURKB | phosphorylation up-regulates → | CDCA8 PSer275 | phosphorylation up-regulates → | CDCA8 | 17483322 | SIGNOR-279506 |
| AURKB | phosphorylation up-regulates → | HASPIN PSer93 | phosphorylation up-regulates → | HASPIN | 21658950 | SIGNOR-263139 |
| AURKB | phosphorylation up-regulates → | SSU72 PSer19 | phosphorylation down-regulates ⊣ | SSU72 | 24149858 | SIGNOR-275529 |
| AURKB | phosphorylation up-regulates → | TP53 PSer215 | phosphorylation down-regulates ⊣ | TP53 | 22611192 | SIGNOR-197602 |
| AURKB | phosphorylation up-regulates → | NDC80 PSer15 | phosphorylation down-regulates ⊣ | NDC80 | 20471944 | SIGNOR-165554 |
| AURKB | phosphorylation up-regulates → | CDCA5 PSer126 | phosphorylation down-regulates ⊣ | CDCA5 | 23901111 | SIGNOR-276123 |
| AURKB | phosphorylation up-regulates → | RACGAP1 PSer187 | phosphorylation up-regulates → | RACGAP1 | 14744859 | SIGNOR-250588 |
| AURKB | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 12686604 | SIGNOR-100165 |
| AURKB | phosphorylation up-regulates → | YY1 PSer184 | phosphorylation up-regulates → | YY1 | 23226345 | SIGNOR-200079 |
| AURKB | phosphorylation up-regulates → | KNL1 PSer60 | phosphorylation down-regulates ⊣ | KNL1 | 20471944 | SIGNOR-165506 |
| AURKB | phosphorylation up-regulates → | H3C1 PSer29 | phosphorylation down-regulates ⊣ | H3C1 | 21282660 | SIGNOR-171717 |
| AURKB | phosphorylation up-regulates → | RPRD1B PSer145 | phosphorylation up-regulates → | RPRD1B | 30518842 | SIGNOR-265499 |
| AURKB | phosphorylation up-regulates → | CHMP4C PSer214 | phosphorylation up-regulates → | CHMP4C | 22724069 | SIGNOR-197971 |
| AURKB | phosphorylation up-regulates → | KNL1 PSer24 | phosphorylation down-regulates ⊣ | KNL1 | 20471944 | SIGNOR-165502 |
| AURKB | phosphorylation up-regulates → | NINL PSer448 | phosphorylation up-regulates → | NINL | 20864540 | SIGNOR-168049 |
| AURKB | phosphorylation up-regulates → | RACGAP1 PThr186 | phosphorylation up-regulates → | RACGAP1 | 14744859 | SIGNOR-250590 |
| AURKB | phosphorylation up-regulates → | INCENP PSer894 | phosphorylation up-regulates → | INCENP | 12925766 | SIGNOR-118015 |
| AURKB | phosphorylation up-regulates → | CHMP4C PSer215 | phosphorylation up-regulates → | CHMP4C | 22422861 | SIGNOR-196728 |
| AURKB | phosphorylation up-regulates → | TP53 PSer269 | phosphorylation down-regulates ⊣ | TP53 | 20959462 | SIGNOR-168745 |
| AURKB | phosphorylation up-regulates → | CDCA2 PSer542 | phosphorylation down-regulates ⊣ | CDCA2 | 32938714 | SIGNOR-274002 |
| AURKB | phosphorylation up-regulates → | H3C1 PSer11 | phosphorylation up-regulates → | H3C1 | 14583461 | SIGNOR-118894 |
| AURKB | phosphorylation up-regulates → | HASPIN PSer143 | phosphorylation up-regulates → | HASPIN | 21658950 | SIGNOR-263138 |
| AURKB | phosphorylation up-regulates → | ZWINT PThr251 | phosphorylation up-regulates → | ZWINT | 21775627 | SIGNOR-265010 |
| AURKB | phosphorylation up-regulates → | HASPIN PSer93 | phosphorylation up-regulates → | HASPIN | 21658950 | SIGNOR-262657 |
| AURKB | phosphorylation up-regulates → | CHMP4C PSer210 | phosphorylation up-regulates → | CHMP4C | 22724069 | SIGNOR-197967 |
| AURKB | phosphorylation up-regulates → | CDCA2 PSer977 | phosphorylation down-regulates ⊣ | CDCA2 | 32938714 | SIGNOR-274004 |
| AURKB | phosphorylation up-regulates → | H3-3A PSer11 | phosphorylation up-regulates → | H3-3A | 12588998 | SIGNOR-98293 |
| AURKB | phosphorylation up-regulates → | TERF1 PSer404 | phosphorylation up-regulates → | TERF1 | 29040668 | SIGNOR-279440 |
| AURKB | phosphorylation up-regulates → | ZWINT PSer250 | phosphorylation up-regulates → | ZWINT | 21775627 | SIGNOR-265009 |
| AURKB | phosphorylation up-regulates → | KIF20A PSer878 | phosphorylation down-regulates ⊣ | KIF20A | 27939310 | SIGNOR-262659 |
| AURKB | phosphorylation up-regulates → | CDCA5 PSer164 | phosphorylation down-regulates ⊣ | CDCA5 | 23901111 | SIGNOR-276113 |
| AURKB | phosphorylation up-regulates → | YY1 PSer180 | phosphorylation up-regulates → | YY1 | 23226345 | SIGNOR-200075 |
| AURKB | phosphorylation up-regulates → | AURKB PThr232 | phosphorylation up-regulates → | AURKB | 14722118 | SIGNOR-121340 |
| AURKB | phosphorylation up-regulates → | KIF4A PThr799 | phosphorylation up-regulates → | KIF4A | 28992084 | SIGNOR-265992 |
| AURKB | phosphorylation up-regulates → | SSU72 PSer19 | phosphorylation down-regulates ⊣ | SSU72 | 24149858 | SIGNOR-275530 |
| AURKB | phosphorylation up-regulates → | CDCA5 PSer139 | phosphorylation down-regulates ⊣ | CDCA5 | 23901111 | SIGNOR-276114 |
| AURKB | phosphorylation up-regulates → | RACGAP1 PSer144 | phosphorylation up-regulates → | RACGAP1 | 14744859 | SIGNOR-250586 |
| AURKB | phosphorylation up-regulates → | DES PSer12 | phosphorylation down-regulates ⊣ | DES | 12686604 | SIGNOR-100107 |
| AURKB | phosphorylation up-regulates → | H3C1 PSer29 | phosphorylation down-regulates ⊣ | H3C1 | 11856369 | SIGNOR-114852 |
| AURKB | phosphorylation up-regulates → | H1-4 PSer27 | phosphorylation up-regulates → | H1-4 | 21511733 | SIGNOR-262658 |
| AURKB | phosphorylation up-regulates → | RACGAP1 PSer185 | phosphorylation up-regulates → | RACGAP1 | 14744859 | SIGNOR-250587 |
| AURKB | phosphorylation up-regulates → | DIAPH2 PSer196 | phosphorylation up-regulates → | DIAPH2 | 21397845 | SIGNOR-172803 |
| AURKB | phosphorylation up-regulates → | INCENP PSer893 | phosphorylation up-regulates → | INCENP | 12925766 | SIGNOR-118011 |
| AURKB | phosphorylation up-regulates → | VIM PSer73 | phosphorylation down-regulates ⊣ | VIM | 12458200 | SIGNOR-96057 |
| AURKB | phosphorylation up-regulates → | TP53 PThr211 | phosphorylation down-regulates ⊣ | TP53 | 22611192 | SIGNOR-197606 |
| AURKB | phosphorylation up-regulates → | MYC PSer67 | phosphorylation up-regulates → | MYC | 32049046 | SIGNOR-279439 |
| AURKB | phosphorylation up-regulates → | RASSF1 PSer207 | phosphorylation down-regulates ⊣ | RASSF1 | 19276349 | SIGNOR-184561 |
| AURKB | phosphorylation up-regulates → | TP53BP1 PSer1342 | phosphorylation up-regulates → | TP53BP1 | 28415769 | SIGNOR-264411 |
| AURKB | phosphorylation up-regulates → | TP53 PSer183 | phosphorylation down-regulates ⊣ | TP53 | 22611192 | SIGNOR-197598 |
| AURKB | phosphorylation up-regulates → | CDCA5 PThr151 | phosphorylation down-regulates ⊣ | CDCA5 | 23901111 | SIGNOR-276117 |
| AURKB | phosphorylation up-regulates → | RACGAP1 PThr145 | phosphorylation up-regulates → | RACGAP1 | 14744859 | SIGNOR-250589 |
| AURKB | phosphorylation up-regulates → | NINL PSer585 | phosphorylation up-regulates → | NINL | 20864540 | SIGNOR-168053 |
| AURKB | phosphorylation up-regulates → | CDCA2 PSer981 | phosphorylation down-regulates ⊣ | CDCA2 | 32938714 | SIGNOR-274001 |
| AURKB | phosphorylation up-regulates → | CDCA5 PSer33 | phosphorylation down-regulates ⊣ | CDCA5 | 23901111 | SIGNOR-276116 |
| AURKB | phosphorylation up-regulates → | PLEKHG6 PThr544 | phosphorylation up-regulates → | PLEKHG6 | 24482237 | SIGNOR-204534 |
| AURKB | phosphorylation up-regulates → | DSN1 PSer109 | phosphorylation down-regulates ⊣ | DSN1 | 20471944 | SIGNOR-165550 |
| AURKB | phosphorylation up-regulates → | DSN1 PSer100 | phosphorylation down-regulates ⊣ | DSN1 | 20471944 | SIGNOR-165546 |
| AURKB | phosphorylation up-regulates → | H3C1 PSer11 | phosphorylation up-regulates → | H3C1 | 12588998 | SIGNOR-98297 |
| AURKB | phosphorylation up-regulates → | NSUN2 PSer139 | phosphorylation down-regulates ⊣ | NSUN2 | 17215513 | SIGNOR-152001 |
| AURKB | phosphorylation up-regulates → | KIF2C PSer95 | phosphorylation up-regulates → | KIF2C | 17567953 | SIGNOR-155890 |
| AURKB | phosphorylation up-regulates → | SKA3 PSer159 | phosphorylation up-regulates → | SKA3 | 22371557 | SIGNOR-262661 |
| AURKB | phosphorylation up-regulates → | ARHGEF2 PSer960 | phosphorylation down-regulates ⊣ | ARHGEF2 | 17488622 | SIGNOR-276062 |
| AURKB | phosphorylation up-regulates → | SHCBP1 PSer634 | phosphorylation up-regulates → | SHCBP1 | 23704356 | SIGNOR-273552 |
| AURKB | phosphorylation up-regulates → | HDAC5 PSer278 | phosphorylation down-regulates ⊣ | HDAC5 | 22865920 | SIGNOR-198650 |
| AURKB | phosphorylation up-regulates → | TP53 PThr284 | phosphorylation down-regulates ⊣ | TP53 | 20959462 | SIGNOR-168749 |
| AURKB | phosphorylation up-regulates → | H3-3A PSer11 | phosphorylation up-regulates → | H3-3A | 14583461 | SIGNOR-118890 |
| AURKB | phosphorylation up-regulates → | RACGAP1 PSer387 | phosphorylation up-regulates → | RACGAP1 | 12689593 | SIGNOR-100569 |
| AURKB | phosphorylation up-regulates → | CDCA5 PSer83 | phosphorylation down-regulates ⊣ | CDCA5 | 23901111 | SIGNOR-276119 |
| AURKB | phosphorylation up-regulates → | DES PSer60 | phosphorylation down-regulates ⊣ | DES | 12686604 | SIGNOR-100111 |
| AURKB | phosphorylation up-regulates → | MYBBP1A PSer1303 | phosphorylation down-regulates ⊣ | MYBBP1A | 20177074 | SIGNOR-163903 |
| AURKB | phosphorylation up-regulates → | KIF2C PSer111 | phosphorylation down-regulates ⊣ | KIF2C | 17567953 | SIGNOR-155894 |
| AURKB | phosphorylation up-regulates → | HASPIN PSer143 | phosphorylation up-regulates → | HASPIN | 21658950 | SIGNOR-262656 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AURKB | phosphorylation → up-regulates | ATM | SIGNOR-177280 |
| AURKB | phosphorylation down-regulates | HDAC9 | SIGNOR-198654 |
| AURKB | phosphorylation → up-regulates | INCENP | SIGNOR-118019 |
| AURKB | phosphorylation → up-regulates | NINL | SIGNOR-168045 |
| AURKB | phosphorylation → unknown | CENPA | SIGNOR-250585 |
| AURKB | phosphorylation → down-regulates activity | CDC20 | SIGNOR-280190 |
| AURKB | phosphorylation → down-regulates activity | CDCA2 | SIGNOR-280191 |
| AURKB | phosphorylation → down-regulates quantity | KIF23 | SIGNOR-280192 |
| AURKB | phosphorylation down-regulates | NDC80 | SIGNOR-165558 |
| AURKB | phosphorylation down-regulates | DES | SIGNOR-100115 |
| AURKB | phosphorylation → up-regulates | CKAP2 | SIGNOR-165410 |
| AURKB | phosphorylation down-regulates | NDC80 | SIGNOR-165562 |
| AURKB | phosphorylation → down-regulates activity | GFAP | SIGNOR-100173 |
| AURKB | phosphorylation → up-regulates activity | PLK1 | SIGNOR-279358 |
| AURKB | phosphorylation → down-regulates activity | POU5F1 | SIGNOR-279592 |
| AURKB | phosphorylation → down-regulates activity | GFAP | SIGNOR-100169 |
| AURKB | phosphorylation → up-regulates activity | ZWINT | SIGNOR-265011 |
| AURKB | phosphorylation → up-regulates activity | SKA1 | SIGNOR-262662 |
| AURKB | phosphorylation → up-regulates activity | CASP2 | SIGNOR-279496 |
| AURKB | phosphorylation down-regulates | KIF2C | SIGNOR-155898 |
| AURKB | phosphorylation down-regulates | HDAC4 | SIGNOR-198646 |
| AURKB | phosphorylation → up-regulates activity | HASPIN | SIGNOR-263137 |
| AURKB | phosphorylation down-regulates | BIRC5 | SIGNOR-154569 |
| AURKB | phosphorylation → up-regulates | MAPRE3 | SIGNOR-202130 |
| AURKB | phosphorylation → up-regulates activity | H3-3A | SIGNOR-70420 |
| AURKB | phosphorylation → unknown | WWC1 | SIGNOR-176363 |
| AURKB | phosphorylation → up-regulates activity | CDCA8 | SIGNOR-279506 |
| AURKB | phosphorylation → up-regulates activity | HASPIN | SIGNOR-263139 |
| AURKB | phosphorylation down-regulates quantity by destabilization | SSU72 | SIGNOR-275529 |
| AURKB | phosphorylation → down-regulates activity | CIT | SIGNOR-279140 |
| AURKB | phosphorylation down-regulates | TP53 | SIGNOR-197602 |
| AURKB | phosphorylation down-regulates | NDC80 | SIGNOR-165554 |
| AURKB | phosphorylation → down-regulates activity | CDCA5 | SIGNOR-276123 |
| AURKB | phosphorylation → up-regulates activity | RACGAP1 | SIGNOR-250588 |
| AURKB | phosphorylation → down-regulates activity | GFAP | SIGNOR-100165 |
| AURKB | phosphorylation → up-regulates | YY1 | SIGNOR-200079 |
| AURKB | phosphorylation down-regulates | KNL1 | SIGNOR-165506 |
| AURKB | phosphorylation → down-regulates activity | H3C1 | SIGNOR-171717 |
| AURKB | phosphorylation → up-regulates activity | RPRD1B | SIGNOR-265499 |
| AURKB | phosphorylation → up-regulates | CHMP4C | SIGNOR-197971 |
| AURKB | phosphorylation down-regulates | KNL1 | SIGNOR-165502 |
| AURKB | phosphorylation → up-regulates | NINL | SIGNOR-168049 |
| AURKB | phosphorylation → up-regulates activity | RACGAP1 | SIGNOR-250590 |
| AURKB | phosphorylation → up-regulates | INCENP | SIGNOR-118015 |
| AURKB | phosphorylation → up-regulates | CHMP4C | SIGNOR-196728 |
| AURKB | phosphorylation down-regulates | TP53 | SIGNOR-168745 |
| AURKB | phosphorylation → down-regulates activity | CDCA2 | SIGNOR-274002 |
| AURKB | phosphorylation → up-regulates activity | H3C1 | SIGNOR-118894 |
| AURKB | phosphorylation → up-regulates activity | HASPIN | SIGNOR-263138 |
| AURKB | phosphorylation → up-regulates activity | ZWINT | SIGNOR-265010 |
| AURKB | phosphorylation → up-regulates activity | HASPIN | SIGNOR-262657 |
| AURKB | phosphorylation → up-regulates | CHMP4C | SIGNOR-197967 |
| AURKB | phosphorylation → down-regulates activity | CDCA2 | SIGNOR-274004 |
| AURKB | phosphorylation → up-regulates activity | H3-3A | SIGNOR-98293 |
| AURKB | phosphorylation → up-regulates activity | TERF1 | SIGNOR-279440 |
| AURKB | phosphorylation → up-regulates activity | ZWINT | SIGNOR-265009 |
| AURKB | phosphorylation → down-regulates activity | KIF20A | SIGNOR-262659 |
| AURKB | phosphorylation → down-regulates activity | CDCA5 | SIGNOR-276113 |
| AURKB | phosphorylation → up-regulates | YY1 | SIGNOR-200075 |
| AURKB | phosphorylation → up-regulates | AURKB | SIGNOR-121340 |
| AURKB | phosphorylation → up-regulates activity | KIF4A | SIGNOR-265992 |
| AURKB | phosphorylation → down-regulates activity | SSU72 | SIGNOR-275530 |
| AURKB | phosphorylation → down-regulates activity | CDCA5 | SIGNOR-276114 |
| AURKB | phosphorylation → up-regulates activity | RACGAP1 | SIGNOR-250586 |
| AURKB | phosphorylation down-regulates | DES | SIGNOR-100107 |
| AURKB | phosphorylation → up-regulates | Histone H3 | SIGNOR-265321 |
| AURKB | phosphorylation → down-regulates activity | H3C1 | SIGNOR-114852 |
| AURKB | phosphorylation → up-regulates quantity by stabilization | H1-4 | SIGNOR-262658 |
| AURKB | phosphorylation → up-regulates activity | RACGAP1 | SIGNOR-250587 |
| AURKB | phosphorylation → up-regulates | DIAPH2 | SIGNOR-172803 |
| AURKB | phosphorylation → up-regulates | INCENP | SIGNOR-118011 |
| AURKB | phosphorylation down-regulates | VIM | SIGNOR-96057 |
| AURKB | phosphorylation down-regulates | TP53 | SIGNOR-197606 |
| AURKB | phosphorylation → up-regulates quantity by stabilization | MYC | SIGNOR-279439 |
| AURKB | phosphorylation down-regulates | RASSF1 | SIGNOR-184561 |
| AURKB | phosphorylation → up-regulates activity | TP53BP1 | SIGNOR-264411 |
| AURKB | phosphorylation down-regulates | TP53 | SIGNOR-197598 |
| AURKB | phosphorylation → down-regulates activity | CDCA5 | SIGNOR-276117 |
| AURKB | phosphorylation → up-regulates activity | RACGAP1 | SIGNOR-250589 |
| AURKB | phosphorylation → up-regulates | NINL | SIGNOR-168053 |
| AURKB | phosphorylation → down-regulates activity | CDCA2 | SIGNOR-274001 |
| AURKB | phosphorylation → down-regulates activity | CDCA5 | SIGNOR-276116 |
| AURKB | phosphorylation → up-regulates | PLEKHG6 | SIGNOR-204534 |
| AURKB | phosphorylation down-regulates | DSN1 | SIGNOR-165550 |
| AURKB | phosphorylation down-regulates | DSN1 | SIGNOR-165546 |
| AURKB | phosphorylation → up-regulates activity | H3C1 | SIGNOR-98297 |
| AURKB | phosphorylation down-regulates | NSUN2 | SIGNOR-152001 |
| AURKB | phosphorylation → up-regulates activity | MAPRE2 | SIGNOR-279591 |
| AURKB | phosphorylation → up-regulates | KIF2C | SIGNOR-155890 |
| AURKB | phosphorylation → up-regulates activity | SKA3 | SIGNOR-262661 |
| AURKB | phosphorylation → down-regulates activity | ARHGEF2 | SIGNOR-276062 |
| AURKB | phosphorylation → up-regulates activity | SHCBP1 | SIGNOR-273552 |
| AURKB | phosphorylation down-regulates | HDAC5 | SIGNOR-198650 |
| AURKB | phosphorylation down-regulates | TP53 | SIGNOR-168749 |
| AURKB | phosphorylation → up-regulates activity | H3-3A | SIGNOR-118890 |
| AURKB | phosphorylation → up-regulates activity | RACGAP1 | SIGNOR-100569 |
| AURKB | phosphorylation → down-regulates activity | CDCA5 | SIGNOR-276119 |
| AURKB | phosphorylation down-regulates | DES | SIGNOR-100111 |
| AURKB | phosphorylation → up-regulates activity | BUB1 | SIGNOR-279010 |
| AURKB | phosphorylation → unknown | MYBBP1A | SIGNOR-163903 |
| AURKB | phosphorylation down-regulates | KIF2C | SIGNOR-155894 |
| AURKB | phosphorylation → up-regulates activity | HASPIN | SIGNOR-262656 |