| Name | AURKB |
| ID | Q96GD4 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 77-327 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | AURKB | Ser331 | HPWVRANsRRVLPPS | phosphorylation up-regulates | 17276342 | SIGNOR-152926 |
| CHEK2 | AURKB | Ser331 | HPWVRANsRRVLPPS | phosphorylation up-regulates activity | 24798733 | SIGNOR-278906 |
| VRK1 | AURKB | – | phosphorylation up-regulates activity | 29340707 | SIGNOR-280160 | |
| AURKB | AURKB | Thr232 | APSLRRKtMCGTLDY | phosphorylation up-regulates | 14722118 | SIGNOR-121340 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | phosphorylation up-regulates → | AURKB PSer331 | phosphorylation up-regulates → | AURKB | 17276342 | SIGNOR-152926 |
| CHEK2 | phosphorylation up-regulates → | AURKB PSer331 | phosphorylation up-regulates → | AURKB | 24798733 | SIGNOR-278906 |
| AURKB | phosphorylation up-regulates → | AURKB PThr232 | phosphorylation up-regulates → | AURKB | 14722118 | SIGNOR-121340 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHEK1 | phosphorylation → up-regulates | AURKB | SIGNOR-152926 |
| CHEK2 | phosphorylation → up-regulates activity | AURKB | SIGNOR-278906 |
| VRK1 | phosphorylation → up-regulates activity | AURKB | SIGNOR-280160 |
| AURKB | phosphorylation → up-regulates | AURKB | SIGNOR-121340 |