Entity Details

Name MASTL_Thr194
ID Q96GX5
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinB/CDK1MASTLThr194NMMDILTtPSMAKPRphosphorylation
up-regulates activity		22354989SIGNOR-243403
PP2CA_R1A_R2A MASTLThr194NMMDILTtPSMAKPRdephosphorylation
down-regulates activity		24391510SIGNOR-276615
CyclinA2/CDK2MASTLThr194NMMDILTtPSMAKPRphosphorylation
up-regulates activity		24391510SIGNOR-276614
CDK1MASTLThr194NMMDILTtPSMAKPRphosphorylation
up-regulates activity		22354989SIGNOR-243414
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinB/CDK1phosphorylation
up-regulates
→
MASTL
PThr194		phosphorylation
up-regulates
→		MASTL22354989SIGNOR-243403
PP2CA_R1A_R2A dephosphorylation
down-regulates
⊣
MASTL
PThr194		dephosphorylation
up-regulates
→		MASTL24391510SIGNOR-276615
CyclinA2/CDK2phosphorylation
up-regulates
→
MASTL
PThr194		phosphorylation
up-regulates
→		MASTL24391510SIGNOR-276614
CDK1phosphorylation
up-regulates
→
MASTL
PThr194		phosphorylation
up-regulates
→		MASTL22354989SIGNOR-243414
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinB/CDK1phosphorylation
→
up-regulates activity 		MASTLSIGNOR-243403
PP2CA_R1A_R2A dephosphorylation
→
down-regulates activity 		MASTLSIGNOR-276615
CyclinA2/CDK2phosphorylation
→
up-regulates activity 		MASTLSIGNOR-276614
CDK1phosphorylation
→
up-regulates activity 		MASTLSIGNOR-243414