| Name | DOCK6 |
| ID | Q96HP0 |
| Role | substrate |
| Enzymatic Domains |
C2 DOCK-type 548-714 PROSITE-ProRule
DOCKER 1587-2023 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | DOCK6 | Ser1194 | GQRSRLAsMLDSDTE | phosphorylation up-regulates activity | 23462102 | SIGNOR-275666 |
| AKT | DOCK6 | Ser1194 | GQRSRLAsMLDSDTE | phosphorylation up-regulates activity | 23462102 | SIGNOR-275667 |
| PP2CA_R1A_R2A | DOCK6 | Ser1194 | GQRSRLAsMLDSDTE | phosphorylation down-regulates activity | 23462102 | SIGNOR-275668 |
| PPP2CA | DOCK6 | Ser1194 | GQRSRLAsMLDSDTE | phosphorylation down-regulates activity | 23462102 | SIGNOR-275669 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | DOCK6 PSer1194 | phosphorylation up-regulates → | DOCK6 | 23462102 | SIGNOR-275666 |
| AKT | phosphorylation up-regulates → | DOCK6 PSer1194 | phosphorylation up-regulates → | DOCK6 | 23462102 | SIGNOR-275667 |
| PP2CA_R1A_R2A | phosphorylation up-regulates → | DOCK6 PSer1194 | phosphorylation down-regulates ⊣ | DOCK6 | 23462102 | SIGNOR-275668 |
| PPP2CA | phosphorylation up-regulates → | DOCK6 PSer1194 | phosphorylation down-regulates ⊣ | DOCK6 | 23462102 | SIGNOR-275669 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → up-regulates activity | DOCK6 | SIGNOR-275666 |
| AKT | phosphorylation → up-regulates activity | DOCK6 | SIGNOR-275667 |
| PP2CA_R1A_R2A | phosphorylation → down-regulates activity | DOCK6 | SIGNOR-275668 |
| PPP2CA | phosphorylation → down-regulates activity | DOCK6 | SIGNOR-275669 |