Entity Details

Name PGAM5
ID Q96HS1
Role phosphatase
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PGAM5ME1Ser336KKIWLVDsKGLIVKGdephosphorylation
up-regulates activity		31735643SIGNOR-275569
PGAM5FUNDC1–dephosphorylation
up-regulates activity		24746696SIGNOR-273654
PGAM5MAP3K5Thr838GINPCTEtFTGTLQYdephosphorylation
up-regulates activity		19590015SIGNOR-277984
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PGAM5dephosphorylation
down-regulates
⊣
ME1
PSer336		dephosphorylation
down-regulates
⊣		ME131735643SIGNOR-275569
PGAM5dephosphorylation
down-regulates
⊣
MAP3K5
PThr838		dephosphorylation
down-regulates
⊣		MAP3K519590015SIGNOR-277984
Regulator Mechanism/Effect Target SIGNOR-ID
PGAM5dephosphorylation
→
up-regulates activity 		ME1SIGNOR-275569
PGAM5dephosphorylation
→
up-regulates activity 		FUNDC1SIGNOR-273654
PGAM5dephosphorylation
→
up-regulates activity 		MAP3K5SIGNOR-277984