| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | WNK4 | Tyr1115 | PVWMNYSySSLCLSS | phosphorylation down-regulates activity | 25805816 | SIGNOR-276895 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | WNK4 PTyr1115 | phosphorylation down-regulates ⊣ | WNK4 | 25805816 | SIGNOR-276895 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → down-regulates activity | WNK4 | SIGNOR-276895 |