Entity Details

Name PBK
ID Q96KB5
Role substrate
Enzymatic Domains
Protein kinase 32-322
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinB/CDK1PBKThr9EGISNFKtPSKLSEKphosphorylation
up-regulates activity
15541388SIGNOR-250720
MAPK1PBK–phosphorylation
up-regulates activity
35546143SIGNOR-279744
CDK1PBKThr9EGISNFKtPSKLSEKphosphorylation
unknown
15541388SIGNOR-130439
SRCPBKTyr272DFDDEAYyAALGTRPphosphorylation
up-regulates quantity by stabilization
27016416SIGNOR-277217
SRCPBKTyr74NPICNDHyRSVYQKRphosphorylation
up-regulates quantity by stabilization
27016416SIGNOR-277218
CyclinB/CDK1PBKThr9EGISNFKtPSKLSEKphosphorylation
unknown
15541388SIGNOR-216896
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinB/CDK1phosphorylation
up-regulates
→
PBK
PThr9
phosphorylation
up-regulates
→
PBK15541388SIGNOR-250720
CDK1phosphorylation
up-regulates
→
PBK
PThr9
phosphorylation
down-regulates
⊣
PBK15541388SIGNOR-130439
SRCphosphorylation
up-regulates
→
PBK
PTyr272
phosphorylation
up-regulates
→
PBK27016416SIGNOR-277217
SRCphosphorylation
up-regulates
→
PBK
PTyr74
phosphorylation
up-regulates
→
PBK27016416SIGNOR-277218
CyclinB/CDK1phosphorylation
up-regulates
→
PBK
PThr9
phosphorylation
down-regulates
⊣
PBK15541388SIGNOR-216896
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinB/CDK1phosphorylation
→
up-regulates activity
PBKSIGNOR-250720
MAPK1phosphorylation
→
up-regulates activity
PBKSIGNOR-279744
CDK1phosphorylation
→
unknown
PBKSIGNOR-130439
SRCphosphorylation
→
up-regulates quantity by stabilization
PBKSIGNOR-277217
SRCphosphorylation
→
up-regulates quantity by stabilization
PBKSIGNOR-277218
CyclinB/CDK1phosphorylation
→
unknown
PBKSIGNOR-216896