| Name | PBK |
| ID | Q96KB5 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 32-322 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | PBK | Thr9 | EGISNFKtPSKLSEK | phosphorylation up-regulates activity | 15541388 | SIGNOR-250720 |
| SRC | PBK | Tyr74 | NPICNDHyRSVYQKR | phosphorylation up-regulates quantity by stabilization | 27016416 | SIGNOR-277218 |
| CyclinB/CDK1 | PBK | Thr9 | EGISNFKtPSKLSEK | phosphorylation unknown | 15541388 | SIGNOR-216896 |
| CDK1 | PBK | Thr9 | EGISNFKtPSKLSEK | phosphorylation unknown | 15541388 | SIGNOR-130439 |
| MAPK1 | PBK | – | phosphorylation up-regulates activity | 35546143 | SIGNOR-279744 | |
| SRC | PBK | Tyr272 | DFDDEAYyAALGTRP | phosphorylation up-regulates quantity by stabilization | 27016416 | SIGNOR-277217 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | PBK PThr9 | phosphorylation up-regulates → | PBK | 15541388 | SIGNOR-250720 |
| SRC | phosphorylation up-regulates → | PBK PTyr74 | phosphorylation up-regulates → | PBK | 27016416 | SIGNOR-277218 |
| CyclinB/CDK1 | phosphorylation up-regulates → | PBK PThr9 | phosphorylation down-regulates ⊣ | PBK | 15541388 | SIGNOR-216896 |
| CDK1 | phosphorylation up-regulates → | PBK PThr9 | phosphorylation down-regulates ⊣ | PBK | 15541388 | SIGNOR-130439 |
| SRC | phosphorylation up-regulates → | PBK PTyr272 | phosphorylation up-regulates → | PBK | 27016416 | SIGNOR-277217 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → up-regulates activity | PBK | SIGNOR-250720 |
| SRC | phosphorylation → up-regulates quantity by stabilization | PBK | SIGNOR-277218 |
| CyclinB/CDK1 | phosphorylation → unknown | PBK | SIGNOR-216896 |
| CDK1 | phosphorylation → unknown | PBK | SIGNOR-130439 |
| MAPK1 | phosphorylation → up-regulates activity | PBK | SIGNOR-279744 |
| SRC | phosphorylation → up-regulates quantity by stabilization | PBK | SIGNOR-277217 |