| Name | EGLN2 |
| ID | Q96KS0 |
| Role | substrate |
| Enzymatic Domains |
Fe2OG dioxygenase 278-376 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK9 | EGLN2 | Ser162 | SSGSGEAsAGLMEEA | phosphorylation up-regulates activity | 27263528 | SIGNOR-279077 |
| PRKCA | EGLN2 | Ser234 | QRAIPPRsIRGDQIA | phosphorylation down-regulates | 18710826 | SIGNOR-180203 |
| PRKCA | EGLN2 | Ser132 | GGDAPSPsKRPWARQ | phosphorylation down-regulates | 18710826 | SIGNOR-180199 |
| MAPK9 | EGLN2 | Ser74 | TATSTTAsPLRDGFG | phosphorylation up-regulates activity | 27263528 | SIGNOR-279078 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK9 | phosphorylation up-regulates → | EGLN2 PSer162 | phosphorylation up-regulates → | EGLN2 | 27263528 | SIGNOR-279077 |
| PRKCA | phosphorylation up-regulates → | EGLN2 PSer234 | phosphorylation down-regulates ⊣ | EGLN2 | 18710826 | SIGNOR-180203 |
| PRKCA | phosphorylation up-regulates → | EGLN2 PSer132 | phosphorylation down-regulates ⊣ | EGLN2 | 18710826 | SIGNOR-180199 |
| MAPK9 | phosphorylation up-regulates → | EGLN2 PSer74 | phosphorylation up-regulates → | EGLN2 | 27263528 | SIGNOR-279078 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK9 | phosphorylation → up-regulates activity | EGLN2 | SIGNOR-279077 |
| PRKCA | phosphorylation down-regulates | EGLN2 | SIGNOR-180203 |
| PRKCA | phosphorylation down-regulates | EGLN2 | SIGNOR-180199 |
| MAPK9 | phosphorylation → up-regulates activity | EGLN2 | SIGNOR-279078 |