| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | NOX5 | Ser544 | RSVTMRKsQRSSKGS | phosphorylation up-regulates | 21297032 | SIGNOR-171847 |
| PRKCA | NOX5 | Ser544 | RSVTMRKsQRSSKGS | phosphorylation up-regulates | 24505490 | SIGNOR-204550 |
| CAMK2A | NOX5 | Ser544 | RSVTMRKsQRSSKGS | phosphorylation unknown | 21642394 | SIGNOR-276331 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | NOX5 PSer544 | phosphorylation up-regulates → | NOX5 | 21297032 | SIGNOR-171847 |
| PRKCA | phosphorylation up-regulates → | NOX5 PSer544 | phosphorylation up-regulates → | NOX5 | 24505490 | SIGNOR-204550 |
| CAMK2A | phosphorylation up-regulates → | NOX5 PSer544 | phosphorylation down-regulates ⊣ | NOX5 | 21642394 | SIGNOR-276331 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → up-regulates | NOX5 | SIGNOR-171847 |
| PRKCA | phosphorylation → up-regulates | NOX5 | SIGNOR-204550 |
| CAMK2A | phosphorylation → unknown | NOX5 | SIGNOR-276331 |
