| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SGK1 | NEDD4L | Ser448 | IRRPRSLsSPTVTLS | phosphorylation down-regulates | 15677482 | SIGNOR-133438 |
| PRKACA | NEDD4L | Ser448 | IRRPRSLsSPTVTLS | phosphorylation down-regulates | 15328345 | SIGNOR-128429 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SGK1 | phosphorylation up-regulates → | NEDD4L PSer448 | phosphorylation down-regulates ⊣ | NEDD4L | 15677482 | SIGNOR-133438 |
| PRKACA | phosphorylation up-regulates → | NEDD4L PSer448 | phosphorylation down-regulates ⊣ | NEDD4L | 15328345 | SIGNOR-128429 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SGK1 | phosphorylation![]() down-regulates | NEDD4L | SIGNOR-133438 |
| PRKACA | phosphorylation![]() down-regulates | NEDD4L | SIGNOR-128429 |