Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
TRPM7	EEF2K	Ser78	SSGSPANsFHFKEAW	phosphorylation up-regulates activity	21112387	SIGNOR-277923
TRPM7	ANXA1	Ser5	sEFLKQAW	phosphorylation up-regulates	24103589	SIGNOR-202804
TRPM7	PLCG2	Ser1164	AVKSGFRsVPLKNGY	phosphorylation up-regulates activity	22759789	SIGNOR-278460
TRPM7	PLCG2	Thr1045	LQPESMRtEKYDPMP	phosphorylation up-regulates activity	22759789	SIGNOR-278459

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
TRPM7	phosphorylation up-regulates →	EEF2K PSer78	phosphorylation up-regulates →	EEF2K	21112387	SIGNOR-277923
TRPM7	phosphorylation up-regulates →	ANXA1 PSer5	phosphorylation up-regulates →	ANXA1	24103589	SIGNOR-202804
TRPM7	phosphorylation up-regulates →	PLCG2 PSer1164	phosphorylation up-regulates →	PLCG2	22759789	SIGNOR-278460
TRPM7	phosphorylation up-regulates →	PLCG2 PThr1045	phosphorylation up-regulates →	PLCG2	22759789	SIGNOR-278459

Regulator	Mechanism/Effect	Target	SIGNOR-ID
TRPM7	phosphorylation → up-regulates activity	EEF2K	SIGNOR-277923
TRPM7	phosphorylation → up-regulates	ANXA1	SIGNOR-202804
TRPM7	phosphorylation → up-regulates activity	PLCG2	SIGNOR-278460
TRPM7	phosphorylation → up-regulates activity	PLCG2	SIGNOR-278459