Entity Details

Name PASK
ID Q96RG2
Role kinase
Enzymatic Domains
PAS 1 119-190
PROSITE-ProRule
PAS 2 335-402
PROSITE-ProRule
Protein kinase 999-1251
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PASKGYS1–phosphorylation
down-regulates activity		16275910SIGNOR-245866
PASKGSK3B–phosphorylation
down-regulates activity		23853095SIGNOR-279639
PASKWDR5Ser49AGHTKAVsSVKFSPNphosphorylation
up-regulates activity		27661449SIGNOR-278266
PASKEEF1A1–phosphorylation
unknown		17595531SIGNOR-245862
PASKPASKThr1161ERGKLFYtFCGTIEYphosphorylation
up-regulates activity		11459942SIGNOR-109481
PASKPASKThr1165LFYTFCGtIEYCAPEphosphorylation
up-regulates activity		11459942SIGNOR-109485
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PASKphosphorylation
up-regulates
→
WDR5
PSer49		phosphorylation
up-regulates
→		WDR527661449SIGNOR-278266
PASKphosphorylation
up-regulates
→
PASK
PThr1161		phosphorylation
up-regulates
→		PASK11459942SIGNOR-109481
PASKphosphorylation
up-regulates
→
PASK
PThr1165		phosphorylation
up-regulates
→		PASK11459942SIGNOR-109485
Regulator Mechanism/Effect Target SIGNOR-ID
PASKphosphorylation
→
down-regulates activity 		GYS1SIGNOR-245866
PASKphosphorylation
→
down-regulates activity 		GSK3BSIGNOR-279639
PASKphosphorylation
→
up-regulates activity 		WDR5SIGNOR-278266
PASKphosphorylation
→
unknown 		EEF1A1SIGNOR-245862
PASKphosphorylation
→
up-regulates activity 		PASKSIGNOR-109481
PASKphosphorylation
→
up-regulates activity 		PASKSIGNOR-109485