| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK4 | TUBGCP6 | Ser1249 | HGHVSDAsISLGEPV | phosphorylation up-regulates activity | 22302995 | SIGNOR-262906 |
| PLK4 | TUBGCP6 | Ser1195 | HGHVSDAsISLGESV | phosphorylation up-regulates activity | 22302995 | SIGNOR-262905 |
| PLK4 | TUBGCP6 | Ser1087 | HGHVSNAsISLGESV | phosphorylation up-regulates activity | 22302995 | SIGNOR-262901 |
| PLK4 | TUBGCP6 | Ser1114 | HGHVSNAsIRVGENV | phosphorylation up-regulates activity | 22302995 | SIGNOR-262902 |
| PLK4 | TUBGCP6 | Ser1176 | ISLGESVsDMAPARP | phosphorylation up-regulates activity | 22302995 | SIGNOR-262904 |
| PLK4 | TUBGCP6 | Ser392 | VSGASPEsISSLLSE | phosphorylation up-regulates activity | 22302995 | SIGNOR-262909 |
| PLK4 | TUBGCP6 | Ser1060 | HGHVSDAsIRVGENV | phosphorylation up-regulates activity | 22302995 | SIGNOR-262900 |
| PLK4 | TUBGCP6 | Ser1465 | PVDPQVQsAADETAV | phosphorylation up-regulates activity | 22302995 | SIGNOR-262908 |
| PLK4 | TUBGCP6 | Ser1168 | HGHVSDAsISLGESV | phosphorylation up-regulates activity | 22302995 | SIGNOR-262903 |
| PLK4 | TUBGCP6 | Ser1437 | RYPDSYEsMSEPPIA | phosphorylation up-regulates activity | 22302995 | SIGNOR-262907 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1249 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262906 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1195 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262905 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1087 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262901 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1114 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262902 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1176 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262904 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer392 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262909 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1060 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262900 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1465 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262908 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1168 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262903 |
| PLK4 | phosphorylation up-regulates → | TUBGCP6 PSer1437 | phosphorylation up-regulates → | TUBGCP6 | 22302995 | SIGNOR-262907 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262906 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262905 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262901 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262902 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262904 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262909 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262900 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262908 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262903 |
| PLK4 | phosphorylation → up-regulates activity | TUBGCP6 | SIGNOR-262907 |
