| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PBK | TP53RK | Ser250 | RLRGRKRsMVG | phosphorylation up-regulates activity | 28412249 | SIGNOR-278236 |
| AKT | TP53RK | Ser250 | RLRGRKRsMVG | phosphorylation up-regulates | 17712528 | SIGNOR-157467 |
| AKT1 | TP53RK | Ser250 | RLRGRKRsMVG | phosphorylation up-regulates | 17712528 | SIGNOR-252503 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PBK | phosphorylation up-regulates → | TP53RK PSer250 | phosphorylation up-regulates → | TP53RK | 28412249 | SIGNOR-278236 |
| AKT | phosphorylation up-regulates → | TP53RK PSer250 | phosphorylation up-regulates → | TP53RK | 17712528 | SIGNOR-157467 |
| AKT1 | phosphorylation up-regulates → | TP53RK PSer250 | phosphorylation up-regulates → | TP53RK | 17712528 | SIGNOR-252503 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PBK | phosphorylation → up-regulates activity | TP53RK | SIGNOR-278236 |
| AKT | phosphorylation → up-regulates | TP53RK | SIGNOR-157467 |
| AKT1 | phosphorylation → up-regulates | TP53RK | SIGNOR-252503 |
