Entity Details

Name SRPK1
ID Q96SB4
Role kinase
Enzymatic Domains
Protein kinase 80-653
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRPK1ARSFphosphorylation
up-regulates activity
21157379SIGNOR-279765
SRPK1SRSF1phosphorylation
up-regulates
10196197SIGNOR-66465
SRPK1SRPK1Ser309 RPNKQEEsESPVERPphosphorylation
up-regulates
22727668SIGNOR-197985
SRPK1SRPK1Ser33 SETQHRGsAPHSESDphosphorylation
up-regulates
22727668SIGNOR-197989
SRPK1SRPK1Thr326 ENPPNKMtQEKLEESphosphorylation
up-regulates
22727668SIGNOR-197993
SRPK1RBM8ASer166RRGGRRRsRSPDRRRphosphorylation
down-regulates
16100109SIGNOR-139551
SRPK1RBM8ASer168GGRRRSRsPDRRRRphosphorylation
down-regulates
16100109SIGNOR-139555
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRPK1phosphorylation
up-regulates
SRPK1
PSer309
phosphorylation
up-regulates
SRPK122727668SIGNOR-197985
SRPK1phosphorylation
up-regulates
SRPK1
PSer33
phosphorylation
up-regulates
SRPK122727668SIGNOR-197989
SRPK1phosphorylation
up-regulates
SRPK1
PThr326
phosphorylation
up-regulates
SRPK122727668SIGNOR-197993
SRPK1phosphorylation
up-regulates
RBM8A
PSer166
phosphorylation
down-regulates
RBM8A16100109SIGNOR-139551
SRPK1phosphorylation
up-regulates
RBM8A
PSer168
phosphorylation
down-regulates
RBM8A16100109SIGNOR-139555
Regulator Mechanism/Effect Target SIGNOR-ID
SRPK1phosphorylation

up-regulates activity
ARSFSIGNOR-279765
SRPK1phosphorylation

up-regulates
SRSF1SIGNOR-66465
SRPK1phosphorylation

up-regulates
SRPK1SIGNOR-197985
SRPK1phosphorylation

up-regulates
SRPK1SIGNOR-197989
SRPK1phosphorylation

up-regulates
SRPK1SIGNOR-197993
SRPK1phosphorylation
img/direct_inhibition.png
down-regulates
RBM8ASIGNOR-139551
SRPK1phosphorylation
img/direct_inhibition.png
down-regulates
RBM8ASIGNOR-139555