| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKDC | DCLRE1C | Ser516 | SSTVAGGsQSPKLFS | phosphorylation up-regulates | 16600297 | SIGNOR-145837 |
| ATM | DCLRE1C | Ser645 | NLSTNADsQSSSDFE | phosphorylation up-regulates | 16874298 | SIGNOR-148323 |
| ATM | DCLRE1C | Ser503 | NDEITDEsLENFPSS | phosphorylation up-regulates | 16874298 | SIGNOR-148315 |
| PRKDC | DCLRE1C | Ser503 | NDEITDEsLENFPSS | phosphorylation up-regulates | 16874298 | SIGNOR-148327 |
| PRKDC | DCLRE1C | Ser645 | NLSTNADsQSSSDFE | phosphorylation up-regulates | 16600297 | SIGNOR-145841 |
| ATM | DCLRE1C | Ser516 | SSTVAGGsQSPKLFS | phosphorylation up-regulates | 16874298 | SIGNOR-148319 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKDC | phosphorylation up-regulates → | DCLRE1C PSer516 | phosphorylation up-regulates → | DCLRE1C | 16600297 | SIGNOR-145837 |
| ATM | phosphorylation up-regulates → | DCLRE1C PSer645 | phosphorylation up-regulates → | DCLRE1C | 16874298 | SIGNOR-148323 |
| ATM | phosphorylation up-regulates → | DCLRE1C PSer503 | phosphorylation up-regulates → | DCLRE1C | 16874298 | SIGNOR-148315 |
| PRKDC | phosphorylation up-regulates → | DCLRE1C PSer503 | phosphorylation up-regulates → | DCLRE1C | 16874298 | SIGNOR-148327 |
| PRKDC | phosphorylation up-regulates → | DCLRE1C PSer645 | phosphorylation up-regulates → | DCLRE1C | 16600297 | SIGNOR-145841 |
| ATM | phosphorylation up-regulates → | DCLRE1C PSer516 | phosphorylation up-regulates → | DCLRE1C | 16874298 | SIGNOR-148319 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKDC | phosphorylation → up-regulates | DCLRE1C | SIGNOR-145837 |
| ATM | phosphorylation → up-regulates | DCLRE1C | SIGNOR-148323 |
| ATM | phosphorylation → up-regulates | DCLRE1C | SIGNOR-148315 |
| PRKDC | phosphorylation → up-regulates | DCLRE1C | SIGNOR-148327 |
| PRKDC | phosphorylation → up-regulates | DCLRE1C | SIGNOR-145841 |
| ATM | phosphorylation → up-regulates | DCLRE1C | SIGNOR-148319 |
