Entity Details

Name IWS1
ID Q96ST2
Role substrate
Enzymatic Domains
TFIIS N-terminal 614-692
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT3IWS1Thr721QRRRMNStGGQTPRRphosphorylation
up-regulates activity		24462114SIGNOR-273495
AKT3IWS1Ser720
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PQRRRMNsTGGQTPRphosphorylation
up-regulates activity		24462114SIGNOR-273496
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT3phosphorylation
up-regulates
→
IWS1
PThr721		phosphorylation
up-regulates
→		IWS124462114SIGNOR-273495
AKT3phosphorylation
up-regulates
→
IWS1
PSer720		phosphorylation
up-regulates
→		IWS124462114SIGNOR-273496
Regulator Mechanism/Effect Target SIGNOR-ID
AKT3phosphorylation
→
up-regulates activity 		IWS1SIGNOR-273495
AKT3phosphorylation
→
up-regulates activity 		IWS1SIGNOR-273496